University of Pittsburgh researchers have identified several triazines that activate HIF1 and increase TPI expression, offering a potential therapeutic approach for Triosephosphate Isomerase Deficiency (TPI Df).
This technology utilizes three-dimensional spheroid culture techniques to transform human pericytes isolated from the aortic adventitia into pluripotent cells.
A University of Pittsburgh researcher has developed a novel approach to increase mRNA-mediated protein expression following nanoparticle liposome-mRNA (NPL-mRNA) delivery.