Description
The main component of this BNP wireless system is a single nanowire sensor that will quantitatively and qualitatively measure BNP levels with high sensitivity and great specificity. The single nanowire sensor fabrication method is already scaleable to the substrate dimensions, and will be ready to mass produce with reproducibility and without a post-assembly process requirement -- a unique advantage over competing designs. Further, this invention utilizes label-free sensing using conducting polymer field effect transistors for cost-effective and simple assays, and a localizing surface modification method using shadow mask for increased flexibility of biosensor development. This invention could be a good candidate for other biomarker sensing applications because the ability to detect extremely low amounts of target biomolecules with high sensitivity down to a single molecule/particle with good specificity and at low cost is keystone requirement to spur growth in the emerging field of biomedical devices. This concept will provide an extremely sensitive transduction mechanism/transducer with enhanced specificity.
IP Status
https://patents.google.com/patent/US20200378920A1