University of Pittsburgh

Connexin Mutation Detection for Lymphatic Variation and Disease

Description

Methods are provided for identifying risk of developing lymphedema, including primary and secondary edema. The methods comprise identifying the presence in a biological sample of a polymorphism in one or more of GJA4, GJA5 and GJC2, resulting in a functional mutation of one or more of connixin 37 (Cx37), Cx40 or Cx47.

IP Status

https://patents.google.com/patent/US9260754B2