Connexin Mutation Detection for Lymphatic Variation and Disease

Description

Methods are provided for identifying risk of developing lymphedema, including primary and secondary edema. The methods comprise identifying the presence in a biological sample of a polymorphism in one or more of GJA4, GJA5 and GJC2, resulting in a functional mutation of one or more of connixin 37 (Cx37), Cx40 or Cx47.

IP Status

https://patents.google.com/patent/US9260754B2

Quick Facts:
Reference Number
01881
Technology Type
Diagnostic/Assay
Technology Subtype
Biomarker
Therapeutic Areas
Cardiovascular
Lead Inventor
David Finegold
Department
GSPH-Human Genetics
All Tech Innovators
Catherine Jackson BatyRobert E. Ferrell Ph.D.David N. Finegold
Date Submitted
2008-12-03
Collections
Cardiometabolic