This technology stands out by enabling seamless compatibility between time-domain and spectral-domain OCT systems, facilitating longitudinal tracking of retinal structure despite device upgrades. Its multi-metric feature extraction and flexible similarity measures accommodate a wide range of imaging modalities and segmentation outputs. The use of Gaussian weighting to reflect operator behavior, combined with robust motion correction, minimizes variability and ensures accurate cross-platform alignment. As a result, clinicians can directly compare historic 2D scans with modern 3D volumes, improving consistency in quantitative analysis and enhancing disease monitoring over time.
Description
This invention is a new technique to solve the backward compatibility problem between TDOCT devices (entrenched technology) and SDOCT devices (new technology with increasing market penetration). SDOCT has higher resolution and faster acquisition times in comparison to TDOCT.
Applications
Cross-vendor OCT image registration
Longitudinal glaucoma progression monitoring
OCT device software upgrades
Clinical trial image harmonization
Teleophthalmology imaging compatibility
Advantages
Enables direct comparison and longitudinal tracking of retinal structure across different OCT platforms
Reduces inter-device measurement variability, improving reliability of RNFL thickness assessments
Enhances registration accuracy through feature-based matching, Gaussian weighting and eye-motion correction
Bridges legacy 2D OCT data with modern 3D volumes, preserving historical patient records
Supports consistent clinical decision-making despite OCT equipment upgrades
Minimizes need for repeat scans, saving time and reducing patient burden
IP Status
https://patents.google.com/patent/US9514513B2
