This invention introduces a novel method for detecting gossypol, a natural toxin found in cottonseeds.
Description
This method utilizes near-infrared emitting lanthanide materials to create luminescence “turn-on” sensors, which are highly sensitive and selective. The invention promises significant improvements in the safety of cottonseed products by providing a reliable and efficient detection mechanism for gossypol.
Applications
• Biomarkers
• Engineering Technology
• Food Safety Testing
• Agri Tech
Advantages
The lanthanide-based luminescence “turn-on” sensors offer several advantages over existing gossypol detection methods. Unlike “turn-off” sensors, which reduce luminescence in the presence of the analyte, these sensors are non-emissive in the absence of gossypol and luminesce only when gossypol is present. This results in higher sensitivity and reliability. Additionally, the sensors can be fabricated in various configurations, such as thin films or solutions, providing flexibility in their application. The fast response time and low limit of detection further enhance their efficiency. Compared to traditional methods like UV-HPLC and FTIR spectroscopy, these sensors require less sample handling and produce easily interpretable data.
Invention Readiness
The technology is currently at the concept stage, with initial demonstrations showing promising results. The sensors have been tested with various background substances, confirming their selectivity and sensitivity. The next steps involve further optimization of the sensing materials and configurations, followed by extensive testing and validation in real-world samples. The invention is supported by partial funding from the Defense Threat Reduction Agency, indicating strong potential for further development and commercialization.
IP Status
https://patents.google.com/patent/US20230011770A1
