University of Pittsburgh

Madin Darby Canine Kidney (MDCK) Cells Expressing the Epithelial Na+ Channel (ENaC)

Description

University of Pittsburgh researchers created clonal lines of MDCK cells expressing alpha, beta and gamma subunits of mouse ENaC. MDCK cells expressing the epithelial sodium channel can be used (i) to study the basic biochemistry of the channel biosynthesis and membrane trafficking, and (ii) to screen chemical or peptide libraries for inhibitors of the channel.

IP Status

Research Tool