University of Pittsburgh researchers have developed a magnesium-based mesh designed to progressively resorb, improving outcomes in dental guided bone regeneration. This innovative mesh provides the necessary form-stability for optimal bone healing while eliminating the need for invasive removal procedures. The unique geometric design of the mesh ensures structural integrity throughout the healing process, making it a significant advancement in dental regenerative medicine.
Description
The magnesium mesh is engineered to provide form-stability and resorbability, crucial for effective dental bone regeneration. Traditional meshes require removal, leading to complications and increased morbidity. This magnesium mesh, however, is designed to degrade progressively, maintaining structural integrity and supporting bone healing without the need for removal. The mesh features redundant design elements to prevent early structural failure and is optimized to degrade at different rates depending on the mechanical stress experienced in situ. This ensures that the mesh supports bone regeneration effectively while resorbing in a controlled manner.
Applications
- Dental bone grafting procedures
- Guided bone regeneration
- Periodontal and oral surgery
- Regenerative medical research
Advantages
The magnesium mesh offers significant advantages over traditional barrier membranes and meshes. Its progressive resorption eliminates the need for invasive removal procedures, reducing patient morbidity and recovery time. The mesh's design ensures structural stability throughout the healing process, even in high-stress areas, and promotes a favorable soft tissue response. This innovation has the potential to improve outcomes in dental bone grafting, particularly in challenging cases with significant bone loss or comorbidities.
Invention Readiness
The magnesium mesh has been validated in preclinical studies with in vivo data, demonstrating its efficacy in supporting bone regeneration and maintaining structural integrity during the healing process.
IP Status
https://patents.google.com/patent/WO2023003808A1
