New Method of Microstreaming

University of Pittsburgh researchers have invented a new method of generating strong acoustic streaming. Using an acoustic signal sent through glass, a strong vortex flow pattern can be produced on a membrane surface resulting in a stable system to enable gas-exchange, potentially as a lifesaving treatment for those in respiratory distress.  

Description

University of Pittsburgh researchers have invented a new method of generating strong acoustic streaming. Using an acoustic signal sent through glass, a strong vortex flow pattern can be produced on a membrane surface resulting in a stable system to enable gas-exchange, potentially as a lifesaving treatment for those in respiratory distress. The novel acoustic streaming flow is relatively inexpensive to fabricate and operate. This system can easily be integrated into many existing microchannel devices to improve gas transfer in microfluidic-based artificial lungs, or to enhance mass transfer previous limited by diffusion within microchannels.

Applications

• Gas transfer towards a micro-artificial lung device ECMO - extracorporeal membrane oxygenation – advanced life support
• Gas exchange requirements in medicine and industry

Advantages

Currently, commonly used methods of microstreaming include bubble microstreaming and sharp edge streaming. However, these have several drawbacks. Bubble microstreaming suffers from stability issues which are overcome by this novel acoustic approach. This approach has been found to exhibit a stronger effect than sharp edge streaming and without the obstruction protruding into the microchannel present in sharp edge streaming. Using an acoustic signal to produce strong co- or counter-rotating vortices via an oscillating membrane, the acoustic streaming flow approach can improve the stability and strength of microfluidics-based gas exchange over existing technologies.

Invention Readiness

A prototype has been produced. Both experimental and computational analysis have shown efficacy. Further work is required to optimize the device and identify more applications.

IP Status

https://patents.google.com/patent/US20240115783A1