Novel Metabolomic Markers in Sepsis and Pneumonia
Description
This invention is related to global metabolomic profiling in subjects hospitalized with pneumonia and sepsis who died at 90 days compared to survivors. These data revealed physiologically relevant metabolites, consistent with known complex processes in early sepsis (e.g., for example, bile acid metabolism, protein catabolism, inflammation, and/or oxidative stress) that were different in patients versus controls. Moreover, the data demonstrate a potential for metabolomic signatures to uncover novel markers in sepsis, though quantification and validation.IP Status
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