Lead Inventor

Soldano Ferrone

Anti-HLA-A mAbs LGIII-147.4.1 and Hybridoma Cell Line

01827

Monoclonal antibody LGIII-147.4.1 targets HLA-A2, enabling selective immune recognition for research tools and MHC studies.

Technology Type: Life Science Research Tool
Technology Subtype: Cell Line
Therapeutic Areas: Immunology
Lead Inventor: Soldano Ferrone
Department: Department of Surgery
All Tech Innovators: Soldano Ferrone
Date Submitted: 2008-09-04

Anti-Beta 2-Microglobulin (beta 2-mu) MoAb NAMB-1 and Hybridoma Cell Line

01818

Monoclonal antibody NAMB-1 targets beta-2 microglobulin in HLA Class I molecules, enabling immune interaction studies.

Technology Type: Life Science Research Tool
Technology Subtype: Cell Line
Lead Inventor: Soldano Ferrone
Department: Department of Surgery
All Tech Innovators: Soldano Ferrone
Date Submitted: 2008-09-03

Peptide Mimic Vaccine System for Inducing CSPG4-Specific Immunity in Melanoma

02347

Peptide mimics P1C21/P3C21 induce CSPG4-specific immunity against melanoma via a human antibody-guided, optimized vaccine approach.

Technology Type: Life Science Research Tool
Technology Subtype: Protein
Lead Inventor: Soldano Ferrone
Department: Department of Surgery
All Tech Innovators: Soldano Ferrone
Xinhui Wang MD, PhD
Date Submitted: 2010-11-24

Anti-ICAM-1 mAb VF27-516 and Hybridoma Cell Line

01829

Monoclonal antibody VF27-516 targets ICAM-1, aiding leukocyte-endothelial interactions research; potential Rhinovirus binding blocker.

Technology Type: Life Science Research Tool
Technology Subtype: Cell Line
Lead Inventor: Soldano Ferrone
Department: Department of Surgery
All Tech Innovators: Soldano Ferrone
Date Submitted: 2008-09-15

Anti-HLA-DR, -DQ and -DP Beta Chains mAb LGII-612.14 and Hybridoma Cell Line

01817

Monoclonal antibody LGII-612.14 targets HLA-DR, -DQ, -DP beta chains; useful research tool for MHC class II studies.

Technology Type: Life Science Research Tool
Technology Subtype: Cell Line
Lead Inventor: Soldano Ferrone
Department: Department of Surgery
All Tech Innovators: Soldano Ferrone
Date Submitted: 2008-09-03

Anti-alpha(v) mAb TP36.1 and Hybridoma Cell Line

01822

Anti-alpha(v) antibody TP36.1 targets human Integrin alpha-5 (αV/CD49e), enabling research tools and hybridoma cell line development.

Technology Type: Life Science Research Tool
Technology Subtype: Cell Line
Lead Inventor: Soldano Ferrone
Department: Department of Surgery
All Tech Innovators: Soldano Ferrone
Date Submitted: 2008-09-03

Anti-Alpha(v) Beta 3 mAb VF27-312 and Hybridoma Cell Line

01824

Monoclonal antibody VF27-312 targets human integrin αVβ3, implicated in tumor angiogenesis; offered as a research tool with hybridoma line.

Technology Type: Life Science Research Tool
Technology Subtype: Cell Line
Lead Inventor: Soldano Ferrone
Department: Department of Surgery
All Tech Innovators: Soldano Ferrone
Date Submitted: 2008-09-04

Anti-Alpha(v) Beta 3 mAb Play a Role in Tumor-Induced Angiogenesis

01823

Anti-αvβ3 antibody therapy impacts tumor-driven angiogenesis by blocking integrin-mediated blood vessel formation.

Technology Type: Life Science Research Tool
Technology Subtype: Cell Line
Lead Inventor: Soldano Ferrone
Department: Department of Surgery
All Tech Innovators: Soldano Ferrone
Date Submitted: 2008-09-03

Monoclonal Antibody Technology for Sensitive ICAM-1 Detection Preserving Cell Adhesion

01825

Non-disruptive ICAM-1 monoclonal antibody detects lesions with preserved adhesion, boosting immunohistochemistry, western blotting, and imaging.

Technology Type: Life Science Research Tool
Technology Subtype: Cell Line
Lead Inventor: Soldano Ferrone
Department: Department of Surgery
All Tech Innovators: Soldano Ferrone
Date Submitted: 2008-09-04

Anti-ICAM-1 mAb CL203.4 and Hybridoma Cell Line

01826

Monoclonal anti-ICAM-1 antibody CL203.4 and hybridoma line for research use; targets leukocyte-endothelium interactions.

Technology Type: Life Science Research Tool
Technology Subtype: Protein
Lead Inventor: Soldano Ferrone
Department: Department of Surgery
All Tech Innovators: Soldano Ferrone
Date Submitted: 2008-09-04

Fully Human Antibodies Targeting Skin Cancer

01794

Fully human antibodies target HMW-MAA for melanoma diagnosis and immunotherapy, with diagnostic kits and broad cancer applications.

Technology Type: Therapeutic Modality
Technology Subtype: Antibody - mAb
Therapeutic Areas: Oncology
Therapeutic Indications: Melanoma
Tags: Immuno-oncology
Lead Inventor: Soldano Ferrone
Department: Department of Surgery
All Tech Innovators: Soldano Ferrone
Xinhui Wang MD, PhD
Technology Readiness Level: 5. Drug candidate created
Date Submitted: 2008-08-08
Collections: Women's & Reproductive Health

Anti-alpha(v) mAb VF33-ST100 and Hybridoma Cell Line

01821

Anti-αV (CD49e) targeting mAb VF33-ST100 for Integrin αV-5; supports research tool use with hybridoma line.

Technology Type: Life Science Research Tool
Technology Subtype: Cell Line
Lead Inventor: Soldano Ferrone
Department: Department of Surgery
All Tech Innovators: Soldano Ferrone
Date Submitted: 2008-09-03

B7-H3 Monoclonal Antibody and Methods of Use Thereof

02369

B7-H3 antibody mAb 376.96 targets malignant cells with high specificity, enabling cancer therapy, diagnostics, and research tools.

Technology Type: Life Science Research Tool
Technology Subtype: Protein
Lead Inventor: Soldano Ferrone
Department: Department of Surgery
All Tech Innovators: Soldano Ferrone
Xinhui Wang MD, PhD
Date Submitted: 2011-01-04

Anti-HLA-A2,B17 MAb HO-2 and Hybridoma Cell Line

01820

HO-2 monoclonal antibody targets human HLA-A2 and B17; useful as a research tool for MHC class I studies.

Technology Type: Life Science Research Tool
Technology Subtype: Cell Line
Lead Inventor: Soldano Ferrone
Department: Department of Surgery
All Tech Innovators: Soldano Ferrone
Date Submitted: 2008-09-03

Monoclonal Antibody and Hybridoma Platform for Sensitive HLA-B27 and Alloantigen Detection

01828

Highly specific monoclonal antibody detects HLA-B27 and related alloantigens with ultra-sensitive, versatile double-determinant immunoassay.

Technology Type: Life Science Research Tool
Technology Subtype: Cell Line
Lead Inventor: Soldano Ferrone
Department: Department of Surgery
All Tech Innovators: Soldano Ferrone
Date Submitted: 2008-09-04

Targeted Combination Therapy for BRAF-Mutated Tumors

02346

Synergistic antibody-BRAF inhibitor therapy targets GRP94-expressing BRAF-mutant tumors, overcoming resistance and reducing metastasis.

Technology Type: Therapeutic Modality
Technology Subtype: Drug Discovery - Target
Therapeutic Areas: Oncology
Therapeutic Indications: Melanoma
Tags: Immuno-oncology
Lead Inventor: Soldano Ferrone
Department: Department of Surgery
All Tech Innovators: Elvira Favoino
Soldano Ferrone
Xinhui Wang MD, PhD
Date Submitted: 2010-11-24