Fluid Removal Algorithm for Acute Kidney Injury
University of Pittsburgh researchers have developed a novel algorithm for determining the optimal rate of fluid removal during continuous kidney replacement therapy in patients with acute kidney injury (AKI). AKI and fluid overload affect more than 50% of intensive care unit (ICU) patients, with a high mortality rate for those requiring dialysis. This Excel-based tool calculates the fluid removal rate using patient-specific parameters, potentially standardizing clinical practices and improving patient outcomes. Once validated through ongoing clinical trials, this algorithm could revolutionize fluid management in critical care settings.
Description
This invention is a decision-support tool designed to aid critical care practitioners in setting the rate of net fluid removal during continuous kidney replacement therapy. The algorithm uses patient-specific data, including predicted body weight and fluid infusion rate, to optimize the fluid removal process. Currently, there is no standardized method for determining this rate, leading to significant variations in clinical practice. By providing a systematic approach, this tool could reduce complications like hypotension, cardiac arrhythmias, and fluid overload, ultimately improving patient survival.Applications
- Kidney replacement therapy (dialysis) in critical care settings- Acute kidney injury management
- Standardizing fluid removal protocols
- Decision-support tool for ICU nurses and physician