GABAA-R Alpha 4 KO Mice

Description

Mice homozygous for this GABAA-R alpha4F allele are viable and fertile. These mutant mice have loxP sites flanking exon 3 of the targeted gene. When bred to Cre-recombinase expressing mice, offspring will have a deletion of exon 3 in the cre expressing tissue(s). These "floxed" mice may be useful in neurological studies including behavior and neurotransmitter function.

IP Status

Research Tool

Quick Facts:
Reference Number
01699
Technology Type
Life Science Research Tool
Technology Subtype
Animal Model
Therapeutic Areas
Mental and Behavioral HealthNeuroscience
Therapeutic Indications
Autism spectrum disorder (ASD)
Lead Inventor
Gregg Homanics
Department
Med-Anesthesiology and Perioperative Medicine
All Tech Innovators
Gregg E. Homanics PhD
Date Submitted
2008-04-16