GABAa Receptor Alpha2 Knock-In Mice

Description

Knock-in mice were constructed with mutations in the α2 (H(270), A(277)) subunits of the GABAA receptor, which resulted in receptors that lacked modulation by ethanol but retained normal responses to GABA in vitro.

IP Status

Research Tool

Quick Facts:
Reference Number
02259
Technology Type
Life Science Research Tool
Technology Subtype
Animal Model
Lead Inventor
Gregg Homanics
Department
Med-Anesthesiology and Perioperative Medicine
All Tech Innovators
Gregg E. Homanics PhD
Date Submitted
2010-07-06