Mathematical Modeling of Inflammation Following Traumatic Brain Injury

Description

The present invention details a method of analysis of injury biomarker data, leading to the creation of patient-specific, mechanistic computational simulations of inflammation and outcome geared towards diagnosis and rational design of therapeutic strategies. This invention, based on the same principles proven in the setting of sepsis/trauma and wound healing, offers the potential to diagnose and prognosticate individual outcomes and to serve as a platform for rational drug/device design for traumatic brain injury.

IP Status

Research Tool

Quick Facts:
Reference Number
01869
Technology Type
Life Science Research Tool
Technology Subtype
Bioinformatics
Therapeutic Areas
Neuroscience
Therapeutic Indications
Other
Lead Inventor
Yoram Vodovotz
Department
Med-Surgery
All Tech Innovators
Gregory M. ConstantineQi MiDavid O. OkonkwoAlexey Yuryevich SolovyevYoram Vodovotz
Date Submitted
2008-11-16
Collections
Regenerative Medicine