University of Pittsburgh

Mitochondria-Targeted Specific Inhibitors of Cytochrome C Peroxidase Activity and Cardiolipin Oxidation as Protectors and Mitigators of Radiation Injury

Description

The present application relates to novel compounds that inhibit cytochrome c (cyt c) peroxidase, compositions comprising these compounds and various uses thereof, for example for protection of cells from apoptosis. In particular, the present application relates to novel imidazole-substituted fatty acids and their use as cyt c peroxidase inhibitors.

IP Status

https://patents.google.com/patent/US9365597B2