Multinuclear-selective MR Spectroscopy Imaging Platform for Single-scan Lipid/water Suppression and Metabolite Mapping
This approach stands apart by delivering comprehensive lipid and water suppression in one acquisition, overcoming limitations of conventional proton MRS. Its simultaneous isolation of low-concentration biomarkers (PUFAs, lactate, choline) in high-fat tissues allows quantitative metabolic mapping with high spatial resolution and reduced scan times. By combining selective multiple-quantum coherence, optimized gradient schemes, and advanced coil designs, the method provides enhanced sensitivity across field strengths and nuclei, facilitating accurate detection of disease-related metabolite alterations and supporting rapid, multi-parametric clinical imaging workflows.