University of Pittsburgh researchers have developed a novel approach for the non-invasive detection and phenotyping of ovarian cancer using liquidbiopsy. This approach allows for the accurate prediction of methylation patterns in new plasma samples, enhancing the sensitivity and specificity of ovarian cancer detection. - Early diagnosis of ovarian cancer.
... , breast cancer, liver cancer, lung cancer, cervical cancer, endometrial cancer, pancreatic cancer, ovarian cancer, gastric cancer, thyroid cancer, glioblastoma, and others). The chromosomal breakpoints of significant numbers of fusion genes have been identified; these breakpoints not only serve as cancer markers but also provide unique opportunities to treat human cancers using genome editing and genome targeting technologies. • Identification and treatment of cancers that involve fusion genes.