Software to Analyze Copy Number Alterations

Description

Innovators at the University of Pittsburgh have designed a novel algorithm that allows the generation of an internal reference signal for copy number alteration detection. This method, referred to as Virtual Normals, allows for the construction of an unbiased reference signal, free of aberrations, from the test samples of a given experiment.This approach has been proven to obtain the best signal-to-noise ratio of alteration values, as validated by an Applied Biosystems Taqman copy number analysis approach.

IP Status

Software

Quick Facts:
Reference Number
02147
Technology Type
Life Science Research Tool
Technology Subtype
Bioinformatics
Tags
GeneticsAlgorithm
Lead Inventor
Robert Sobol
Department
Med-Pharmacology and Chemical Biology
All Tech Innovators
Uma R. ChandranWilliam A. LaFramboise Ph.D.Aleksandr LisovichMaureen Ann LyonsIan F. Pollack MDRobert William Sobol Jr
Date Submitted
2010-02-17