Description
Biomarkers for Infant Brain Injury Score (BIBIS) is a rapid multiplex immunoassay of four blood biomarkers coupled with a multivariate algorithm. The BIBIS assay is performed on a proprietary microporous silicon substrate which enables the rapid multiplex analysis of biomarkers from small volumes of biological samples. The resultant biomarker concentrations are processed using a multivariate algorithm to provide a score that is highly predictive of ICH. BIBIS was prospectively tested on 599 patients and demonstrated 89.3% sensitivity and 48.0% specificity for ICH. This technology uniquely enables rapid, automated multiplex biomarker testing, making it conducive for use in acute care settings where rapid diagnosis is important.
IP Status
https://patents.google.com/patent/US20210382073A1