University of Pittsburgh
Cardiometabolic - University of Pittsburgh

Cardiometabolic

Includes cardiometabolic-related technologies including indications like NASH, Cirrhosis, CKD, nephrosis, and diabetic kidney disease.
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Novel Continuous Monitoring of Cardiac Health
University of Pittsburgh researchers have developed a novel approach to continuously monitor blood pressure (BP).
Digital Health
Healthcare Delivery
Cardiovascular
Machine learningCardiologyCardiovascular Disease
Pengfei Zhou
SCI-Informatics and Networked Systems
2024-11-19
Machine Learning-Based Cardiovascular Risk Prediction Tool for Personalized 10-Year CVD Estimates in Midlife Women
This tool leverages longitudinal data from the Study of Women’s Health Across the Nation (SWAN) to deliver personalized 10-year cardiovascular risk estimates for midlife women.
Life Science Research Tool
Bioinformatics
Cardiovascular
Ziyuan Wang
GSPH-Epidemiology
2025-04-11
Post-Cardiac Arrest Classification Mobile and Web App
University of Pittsburgh researchers are developing a mobile and web application to assist clinicians in real-time calculation of the Pittsburgh Cardiac Arrest Category (PCAC) score.
Diagnostic/Assay
Other Diagnostic/Assay
Cardiovascular
Other
Ankur Doshi
Med-Emergency Medicine
2022-05-19
Novel Mouse Models of Rare Genetic Disorder
University of Pittsburgh researchers have used the CRISPR technology to create a new mouse model for a rare, recessive metabolic disorder.
Life Science Research Tool
Animal Model
Endocrinology and Metabolic DiseasesRare Diseases
Rare disease
Michael Palladino
Med-Pharmacology and Chemical Biology
2020-10-21
AI-Powered Precision Stroke Care
NeuroSmart is an AI-driven clinical decision support system (CDSS) designed to optimize stroke management by providing personalized, real-time diagnostic and treatment recommendations.
Digital Health
Clinical Decision Support
Cardiovascular
Stroke
Artificial intelligence (AI)Machine learningAlgorithm
Mohamed Doheim
Med-Neurology
2025-03-07
Novel Research Model for Liver Dysfunction
University of Pittsburgh researchers have developed a novel in vitro model of metabolic dysfunction-associated steatotic liver disease (MASLD) in patients with genetic mutations (TM6SF2-167K).
Life Science Research Tool
Cell Line
Hepatology
Cirrhosis
Drug Discovery - TargetLife Science
Alejandro Soto Gutierrez
Med-Pathology
2024-07-17
Personalized Prevention of Intraoperative Hypotension
University of Pittsburgh and Carnegie Mellon University researchers have developed a novel approach to reducing the risk of intraoperative hypotension (IOH).
Digital Health
Clinical Decision Support
Cardiovascular
Other
Precision medicineAlgorithmSurgery
Michael Schnetz
Med-Anesthesiology and Perioperative Medicine
2021-02-08
Small Molecule Allosteric Modulators of Class B GPCRs in the PTHR and Method to Identify Them
Parathyroid hormone (PTH) type 1 receptor (PTHR) is an indispensable G protein-coupled receptor (GPCR) of class B that functions to regulate blood levels of vitamin D, calcium, and phosphate ions in the body, as well as bone turnover.
Therapeutic Modality
Small Molecule
Endocrinology and Metabolic DiseasesMusculoskeletal
Ieva Sutkeviciute
Med-Pharmacology and Chemical Biology
2020-11-19
Novel Animal Model for High-Throughput Screening of Anti-Aging and Metabolic Disease Drugs
This invention is a novel, in vivo, luciferase-based reporter animal model that provides a dynamic, quantifiable measure of methionine metabolism in living organisms.
Life Science Research Tool
Animal Model
Endocrinology and Metabolic Diseases
Other
AgingPlatform TechnologyDrug Repurposing
Sudipta Pathak
Med-Aging Institute
2025-09-14
Novel Therapy for Chondrocyte Aging and Osteoarthritis
University of Pittsburgh researchers have developed a novel therapy for chondrocyte aging and, ultimately, osteoarthritis (OA).
Therapeutic Modality
Small Molecule
CardiovascularMusculoskeletal
Atherosclerotic diseaseHeart failureOsteoarthritis
Drug Discovery - TargetLife Science
Hang Lin
Med-Orthopedic Surgery
2024-12-11
Vasculogenic Reprogramming for Diabetic Wound Healing and Ischemic Tissue Regeneration
The University of Pittsburgh has developed a technology that enhances in vivo vasculogenic reprogramming using Tissue Nanotransfection (TNT) to deliver specific transcription factors.
Therapeutic Modality
Gene Therapy - DNA
Endocrinology and Metabolic Diseases
Diabetes
Chandan Sen
Med-Surgery
2024-09-16
Advanced Laser-Assisted Fabrication of Mesoporous, Compliance-Matched, and Drug-Eluting Vascular Grafts
University of Pittsburgh researchers have developed an innovative additive and subtractive laser-assisted rolling fabrication technique to create mesoporous, compliance-matched, and drug-eluting vascular grafts.
Engineering Technology
Other Engineering Technology
Cardiovascular
Atherosclerotic diseaseOther
Cardiovascular DiseaseEngineeringTherapeutic Medical Device
Jonathan Vande Geest
Bioengineering
2024-07-26
Handheld Oscillating Device of Vascular Interventions
University of Pittsburgh researchers have developed a novel handheld oscillating wire torquing device to assist the delivery of interventional guidewires.
Medical Device
Surgical Medical Device
Cardiovascular
Atherosclerotic disease
Catalin Toma
Med-Medicine
2023-12-13
Proactive AI System for Real-Time Prediction and Management of Anesthesia-Induced Hypotension
This is an advanced computational system employing a highly-optimized machine-learning model to provide early and precise prediction of mean blood pressure (MBP) and the associated risk of Post-Induction Hypotension (PIH) in surgical patients.
Digital Health
Clinical Decision Support
Cardiovascular
Other
5
Artificial intelligence (AI)Machine learningPrecision medicine
Harikesh Subramanian
Med-Anesthesiology and Perioperative Medicine
2023-11-29
AI for Vascular Calcification Risk Assessment
University of Pittsburgh researchers have developed a novel tool to classify vascular calcification as clinical risk.
Digital Health
Clinical Decision Support
Cardiovascular
Atherosclerotic disease
4
CardiologyClinical Decision SupportLife Science
Mehdi Ramezanpour Koomleh
Mechanical Engineering and Materials Science
2023-10-12