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Next-Generation Long-Lasting Soluble CD4-D1 Domains as HIV Entry Inhibitors
06603
University of Pittsburgh researchers have engineered a next-generation soluble CD4-D1 domain with enhanced stability and extended in vivo half-life, designed to serve as a potent HIV entry inhibitor.
Therapeutic Modality
Protein
Infectious Disease
HIV
Wei Li
Med-Medicine
2024-01-08
Tenofovir Spray Drying Sachet Enema Powder Formulation for HIV Prevention
05906
Researchers at Pitt have developed a rectal microbicide product in the form of a hypotonic liquid enema containing the antiretroviral drug tenofovir (TFV) for HIV prevention.
Therapeutic Modality
Drug Delivery / Formulation
Infectious Disease
HIV
Lisa Rohan
Pharm-Pharmaceutical Science
2021-12-03
A Novel Vaginal Film Platform for Sustained Drug Delivery
05770
University of Pittsburgh researchers have developed a sustained release vaginal film for the simultaneous protection against HIV and unintended pregnancy.
Therapeutic Modality
Drug Delivery / Formulation
Infectious DiseaseReproductive Health
4HIVObstetricsGynecological disorder
Lisa Rohan
Pharm-Pharmaceutical Science
2021-07-23
    • Technology Type
      • 10
        Therapeutic Modality
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    • Technology Subtype
      • 4
        Drug Delivery / Formulation
      • 2
        Protein
      • 2
        Small Molecule
      • 1
        Antibody - Fab
      • 1
        Other Therapeutic Modality
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    • Therapeutic Areas
      • 10
        Infectious Disease
      • 1
        Oncology
      • 1
        Reproductive Health
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    • Therapeutic Indications
      • 76
        Other
      • 25
        Solid tumor
      • 23
        Alzheimer's Disease
      • 20
        Breast cancer
      • 15
        Prostate cancer
      • 10
        HIV
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    • Tags
      • 1
        Cell therapy
      • 1
        Immuno-oncology
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    • Lead Inventor
      • 4
        Lisa Rohan
      • 3
        Thomas Smithgall
      • 1
        Dimiter Dimitrov
      • 1
        Robbie Mailliard
      • 1
        Wei Li
      • Add ...
    • Department
      • 4
        Pharm-Pharmaceutical Science
      • 3
        Med-Microbiology and Molecular Genetics
      • 2
        Med-Medicine
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    • All Tech Innovators
      • 4
        Lisa Cencia Rohan
      • 3
        Thomas E. Smithgall
      • 2
        John W. Mellors
      • 1
        Allen B. Reitz
      • 1
        Barry R. O'Keefe
      • Add ...
    • Date Submitted
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