This technology employs a composite structure that integrates less than 10% mass of superelastic nitinol connectors with over 80% mass of biodegradable metals such as magnesium, supported by thin layers of biodegradable polymers like polyesters or PEUU. The design features mechanically clamped or threaded connections, with polymers applied via electrospinning, which creates a collapsible framework easily delivered through catheter-based systems. When cooled below 5°C, the system is inserted in its compressed form and, upon reaching body temperature, it recovers to its preformed geometry, providing temporary structural support and promoting gradual tissue integration as the biodegradable components are safely resorbed.

Description

This approach is differentiated by its unique blend of mechanical resilience and controlled bioabsorption. The minimal use of permanent metal reduces long-term residue and potential complications, while the temperature-sensitive expansion ensures minimally invasive delivery and precise deployment. Additionally, the fusion of mechanical clamping with advanced material deposition techniques allows for customizable geometry and tailoring of mechanical properties, ultimately offering a versatile solution that meets the diverse demands of vascular and other therapeutic applications in both pediatric and geriatric populations.

Applications

Cardiovascular stent grafts
Intracranial aneurysm stents
Septal defect closure devices
IVC filters
Pediatric heart valves

Advantages

Provides temporary scaffolding that supports gradual tissue integration and healing.
Enables self-expansion through superelastic nitinol components for reliable deployment.
Utilizes an ultra-low profile design suited for minimally invasive, catheter-based delivery.
Offers customizable mechanical properties and geometry for diverse clinical applications.
Minimizes long-term implant residue, reducing risks associated with permanent implants.

IP Status

https://patents.google.com/patent/US20220160526A1

Superelastic, Bioabsorbable Endovascular Devices