A team of researchers from the University of Pittsburgh have identified the cause of a new neurological syndrome and a potential therapeutic target for its treatment.
This approach employs targeted reduction of β-catenin expression or activity in the liver to alleviate porphyria by correcting dysregulated heme biosynthesis.
University of Pittsburgh researchers have designed and synthesized novel carbamates to target the potassium channels (K-channels) in auditory synapses, a novel target for the treatment of tinnitus.
This novel combinatorial therapeutic method pairs allogenic stem cell transplantation with an advanced viral vector-mediated gene therapy to boost the crucial GALC enzyme expression.
University of Pittsburgh and Cedars-Sinai Medical Center scientists have developed a novel MRI (magnetic resonance imaging) method, 4D Oxy-wavelet MRI, to monitor mitochondrial function in live ...
This technology comprises a novel class of phenyl indole compounds that selectively inhibit p97 ATPase, a protein critically involved in cellular protein quality control and implicated in cancer ...
