New Permanent Treatment for Cerebral Aneurysms

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Small Molecule Inhibitor Therapy to Prevent Aneurysm Formation, Growth, and Rupture

05390

Cerebral aneurysms are focal dilations of cerebral arteries that are present in approximately 3-5% of the general population.

New research shows that small molecule inhibitors targeting the platelet-driven CXCL7-CXCR1/2 inflammatory pathway can be used to prevent cerebral aneurysm formation and rupture.

· Preventing the formation, growth, and rupture of cerebral aneurysms.

Robert Friedlander

Therapeutic Modality

Small Molecule

Cardiovascular Neuroscience

Small molecule

2020-05-30

Bioabsorbable Metallic Alloy Coils for Aneurysm Treatment

05854

Arterial dilation in the brain results in a cerebral aneurysm at risk of rupture, which can result in catastrophic life-long consequences or death.

Cerebral aneurysm.

University of Pittsburgh researchers have developed new bioabsorbable metallic alloy coils coated with polyurethane based on fatty amide functional groups for treating various aneurysms.

William Wagner

Medical Device

Implantable Medical Device

Nephrology Neuroscience

2021-10-25

Wireless Flow Sensor to Monitor Aneurysms

03488

When blood vessel walls weaken over time, localized enlargement of a blood vessel can form an aneurysmal sac.

Rupturing of this sac can have devastating consequences, and mortality rates of up to 50% in cerebral aneurysms are reported.

Such wireless monitoring could allow for non-invasive continuous monitoring of blood flow within the aneurysm sac during and after surgical intervention.

Young Chun

Medical Device

Monitoring Medical Device

Cardiovascular

Implantable Medical Device Life Science

2015-01-14

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