New Permanent Treatment for Cerebral Aneurysms
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Neuroscience
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Cerebral aneurysms are focal dilations of cerebral arteries that are present in approximately 3-5% of the general population. New research shows that small molecule inhibitors targeting the platelet-driven CXCL7-CXCR1/2 inflammatory pathway can be used to prevent cerebral aneurysm formation and rupture. · Preventing the formation, growth, and rupture of cerebral aneurysms.
Arterial dilation in the brain results in a cerebral aneurysm at risk of rupture, which can result in catastrophic life-long consequences or death. Cerebral aneurysm. University of Pittsburgh researchers have developed new bioabsorbable metallic alloy coils coated with polyurethane based on fatty amide functional groups for treating various aneurysms.
One out of every 20 deaths in the United States is caused by stroke. If administered quickly, surgery or clot-dissolving agents can improve the odds of survival.
- 3Therapeutic Modality
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- 2Small Molecule
- 1Implantable Medical Device
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- 10Cardiovascular
- 4Neuroscience
- 2Musculoskeletal
- 1Gastroenterology
- 1Nephrology
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- 1Biomaterial
- 1Small molecule
- 1Tissue engineering
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- 1Alan Boruch
- 1Elias Aizenman
- 1Robert Friedlander
- 1William Wagner
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- 1Bioengineering
- 1Med-Neurobiology
- 1Med-Neurological Surgery
- 1Med-Pharmacology and Chemical Biology
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- 2Kamil W. Nowicki
- 1Alan V. Boruch
- 1Carlos Jaime Camacho
- 1Elias Aizenman
- 1Michael P. D'Angelo
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