Novel Diagnostic Biomarker for Alzheimer's Disease06770Ultrasensitive CSF assay detects early pre-tangle soluble tau assemblies, enabling earlier Alzheimer’s diagnosis and targeted therapies.Technology TypeDiagnostic/AssayTechnology SubtypeIn vitro DiagnosticTherapeutic AreasNeuroscienceTherapeutic IndicationsAlzheimer's DiseaseLead InventorThomas KarikariDepartmentMed-PsychiatryAll Tech InnovatorsEric E. AbrahamsonMilos Dragan Ikonomovic MDThomas K. KarikariDate Submitted2024-06-10
Heterocyclic Compounds for Imaging Aggregated Tau06319New indole-based PET tracers selectively image 4R-tau in PSP/CBD, aiding early non-Alzheimer’s tauopathy diagnosis and therapy monitoring.Technology TypeMedical DeviceTechnology SubtypeDiagnostic ImagingTherapeutic AreasNeuroscienceTherapeutic IndicationsAlzheimer's DiseaseTagsDiagnostic ImagingLife ScienceLead InventorJeffrey StehouwerDepartmentMed-RadiologyAll Tech InnovatorsThomas GrahamRobert H. MachChester A. Mathis Jr., Ph.D.Date Submitted2023-02-28
Extracorporeal Human Brain Perfusion Platform06814Ex vivo human brain perfusion platform enables live brain tissue stimulation, recording, and analysis under near-physiological conditions.Technology TypeLife Science Research ToolTechnology SubtypeOther Life Science Research ToolTherapeutic AreasNeuroscienceTagsBrain-computer interfaceLife ScienceLead InventorPascal ZinnDepartmentMed-Neurological SurgeryAll Tech InnovatorsPascal Oliver ZinnDate Submitted2024-07-19
A Novel Approach to Treating Autoimmune Diseases by Modulating Immune Cell Proliferation07129PIKFYVE inhibitors boost Treg cells, curb Th17 differentiation, restoring immune balance to treat autoimmune diseases.Technology TypeTherapeutic ModalityTechnology SubtypeDrug Discovery - TargetTherapeutic AreasNeuroscienceImmunologyTherapeutic IndicationsMultiple Sclerosis (MS)Autoimmune encephalitis (AIE)TagsAutoimmunePlatform TechnologyPersonalized MedicineLead InventorWilliam HawseDepartmentMed-ImmunologyAll Tech InnovatorsWilliam F. HawseTechnology Readiness Level4. Pre-clinical developmentDate Submitted2025-03-27
TDP-43 Targeting Antibodies for Diagnosing Neurodegenerative Diseases07105Novel antibodies target TDP-43 for early, non-invasive diagnosis of AD, ALS, PD, FTD, and related conditions.Technology TypeTherapeutic ModalityTechnology SubtypeAntibody - mAbTherapeutic AreasNeuroscienceTherapeutic IndicationsParkinson's DiseaseAmyotrophic lateral sclerosis (ALS)Alzheimer's DiseaseTagsIn Vitro DiagnosticLead InventorThomas KarikariDepartmentMed-PsychiatryAll Tech InnovatorsThomas K. KarikariXuemei ZengDate Submitted2025-03-04
Automated Tool for Infant Facial Action Unit Detection05739Infant AFAR automates infant facial action unit detection, enabling real-time, cross-age AU analysis with CNN-based accuracy.Technology TypeDigital HealthTechnology SubtypeClinical Decision SupportTherapeutic AreasNeuroscienceLead InventorItir Onal ErtugrulDepartmentPsychologyAll Tech InnovatorsAmy AhnManeesh BilalpurJeffrey F. CohnDate Submitted2021-06-23
Next-Generation Bio-Adaptive Stent for Safer Organ Repair07303Bio-adaptive hybrid stent combines strong initial support with bioresorbable components, reducing migration and removal needs.Technology TypeMedical DeviceTechnology SubtypeImplantable Medical DeviceTherapeutic AreasNeuroscienceCardiovascularTherapeutic IndicationsStrokeTagsImplantable Medical DeviceMaterial ScienceLead InventorMohamed DoheimDepartmentMed-NeurologyAll Tech InnovatorsMohamed DoheimRaul Gomes NogueiraDate Submitted2025-08-24CollectionsRegenerative MedicineCardiometabolic
Novel Biomarker for Cervical Spondylotic Myelopathy07261Blood-based biomarker panel with ML predicts CSM diagnosis, severity, prognosis, and treatment response, reducing invasive testing.Technology TypeDiagnostic/AssayTechnology SubtypeBiomarkerTherapeutic AreasNeuroscienceTagsAgingBiomarkerClinical Decision SupportLead InventorNitin AgarwalDepartmentMed-Neurological SurgeryAll Tech InnovatorsNitin AgarwalSameer AgnihotriDavid Kojo HamiltonDate Submitted2025-07-24
AI-Driven Precision Dosing and Survival Analytics for Personalized Brain Radiosurgery07224AI-driven personalized brain radiosurgery dosing and survival analytics with guardrails for precise, safer, rapid clinical guidance.Technology TypeDigital HealthTechnology SubtypeClinical Decision SupportTherapeutic AreasNeuroscienceOncologyTherapeutic IndicationsBrain cancer - OtherGlioblastomaSolid tumorTagsArtificial intelligence (AI)Machine learningSurgeryLead InventorJheremy S. ReyesAll Tech InnovatorsConstantinos George HadjipanayisL Dade LunsfordAjay NiranjanTechnology Readiness Level4. Prototype testing and refinementDate Submitted2025-06-16CollectionsHealthcare AI
Novel Classification System for Temporal Lobe SEEG Explorations06813Proposes a standardized SEEG classification for temporal lobe epilepsy, improving implantation accuracy, planning, and seizure outcomes.Technology TypeMedical DeviceTechnology SubtypeImplantable Medical DeviceTherapeutic AreasNeuroscienceLead InventorArka MallelaDepartmentMed-Neurological SurgeryAll Tech InnovatorsThandar AungJorge A. Gonzalez-MartinezArka Narayana MallelaDate Submitted2024-07-18
Dual Modality Micro-Invasive Neural Probes for Simultaneous Neurochemical and Electrophysiological In Deep Brain Structures06771Dual-modality micro-invasive neural probe enables simultaneous neurochemical and electrophysiological recording across deep brain regions.Technology TypeMedical DeviceTechnology SubtypeMonitoring Medical DeviceTherapeutic AreasNeuroscienceLead InventorHelen SchwerdtDepartmentBioengineeringAll Tech InnovatorsUsamma AmjadJiwon ChoiHelen SchwerdtDate Submitted2024-06-10
Novel Biomarker Tools for Tauopathies06769Antibody-based blood tests detect phosphorylated tau, enabling early tauopathy diagnosis and tracking treatment responses.Technology TypeDiagnostic/AssayTechnology SubtypeIn vitro DiagnosticTherapeutic AreasNeuroscienceTherapeutic IndicationsAlzheimer's DiseaseLead InventorThomas KarikariDepartmentMed-PsychiatryAll Tech InnovatorsThomas K. KarikariXuemei ZengDate Submitted2024-06-06
Innovative Low-Profile Deployable and Retrievable Epidural Lead Array System for Pain Management06614Ultra-thin, deployable epidural lead array enables safer, retrievable spinal cord stimulation with larger contact area for pain.Technology TypeMedical DeviceTechnology SubtypeSurgical Medical DeviceTherapeutic AreasNeuroscienceTherapeutic IndicationsPainLead InventorTrent EmerickDepartmentMed-Anesthesiology and Perioperative MedicineAll Tech InnovatorsHassan Beheshti SereshtGaurav ChauhanYoungjae Jae ChunDate Submitted2024-01-17
Innovative Deep Brain Stimulation for Upper-Limb Motor Control and Speech Recovery06571Potentiates motor output via targeted motor thalamus stimulation, aiding upper-limb control and speech recovery post-injury.Technology TypeMedical DeviceTechnology SubtypeImplantable Medical DeviceTherapeutic AreasNeuroscienceLead InventorElvira PirondiniDepartmentMed-Physical Medicine & RehabilitationAll Tech InnovatorsDonald James CrammondArianna DamianiJorge A. Gonzalez-MartinezDate Submitted2023-11-16
Biased GPCR Ligands as a Therapeutic Intervention Strategy for Alzheimer's Disease06184Biased GPCR ligands selectively block β-arrestin signaling, reduce amyloid pathology, and preserve safety in Alzheimer's models.Technology TypeTherapeutic ModalityTechnology SubtypeDrug Discovery - TargetTherapeutic AreasNeuroscienceTherapeutic IndicationsAlzheimer's DiseaseLead InventorAmantha ThathiahDepartmentMed-NeurobiologyAll Tech InnovatorsYunhong HuangAmantha ThathiahDate Submitted2022-10-05
Optogenetic Induction of Neurodegenerative Disease Pathologies04130Blue-light induced fusion proteins trigger controllable TDP-43/alpha-synuclein/Tau aggregation, modeling neurodegeneration for high-throughput screening.Technology TypeLife Science Research ToolTechnology SubtypeNucleic AcidTherapeutic AreasNeuroscienceTherapeutic IndicationsAmyotrophic lateral sclerosis (ALS)Alzheimer's DiseaseTagsAgingGeneticsPlatform TechnologyLead InventorChristopher DonnellyDepartmentMed-NeurobiologyAll Tech InnovatorsChristopher James DonnellyJacob R. MannDate Submitted2017-01-15
AutoOMR: Automated Optomotor Reflex Behavior Detection07566Automated optomotor reflex analysis using webcam and deep learning for standardized, scalable, cost-efficient behavioral endpoint.Technology TypeLife Science Research ToolTechnology SubtypeOther Life Science Research ToolTherapeutic AreasNeuroscienceOphthalmologyTagsLife ScienceLead InventorShaohua PiDepartmentMed-OphthalmologyAll Tech InnovatorsShaohua PiLingyun WangDate Submitted2026-04-21
Biodegradable Polymer Conduits for Controlled and Sustained Drug Delivery07365Biodegradable PLGA/PLA nerve conduits with double-walled microspheres enable 60+ day, controlled drug release for enhanced regeneration.Technology TypeMedical DeviceTechnology SubtypeImplantable Medical DeviceTherapeutic AreasNeuroscienceTagsBiomaterialPolymerRegenerative medicineLead InventorKacey MarraDepartmentMed-Plastic SurgeryAll Tech InnovatorsDzana KatanaKacey Gribbin MarraTechnology Readiness Level3. Prototype developmentDate Submitted2025-10-06CollectionsRegenerative MedicineHealthcare AI
Restorative Neurophysiology: A System for Re-achieving Previous Neurological States07059Restores a personalized prior brain state using baseline EEG and adaptive TACS, enabling non-invasive, closed-loop neural restoration.Technology TypeMedical DeviceTherapeutic AreasNeuroscienceMental and Behavioral HealthTherapeutic IndicationsDepressionTagsPrecision medicineBrain-computer interfaceLead InventorGreg SiegleDepartmentMed-PsychiatryAll Tech InnovatorsGreg Jeremy Siegle Ph.D.Technology Readiness Level3. Prototype developmentDate Submitted2025-02-04
High-Density Micro-Invasive Array for Brain Monitoring06812High-density, dissolvable carbon-fiber brain electrodes enable simultaneous neurochemical and electrical monitoring for deep-brain studies and stimulation.Technology TypeMedical DeviceTechnology SubtypeImplantable Medical DeviceTherapeutic AreasNeuroscienceTagsImplantable Medical DeviceLife ScienceLead InventorHelen SchwerdtDepartmentBioengineeringAll Tech InnovatorsShreya MahajanHelen SchwerdtRitesh ShrivastavDate Submitted2024-07-18
Streamlined Resource–Efficient Assay for Amyloid-β06792A streamlined IP-MS assay uses a common buffer to quantify plasma amyloid-β biomarkers, enabling affordable, noninvasive AD monitoring.Technology TypeDiagnostic/AssayTechnology SubtypeBiomarkerTherapeutic AreasNeuroscienceTherapeutic IndicationsAlzheimer's DiseaseTagsIn Vitro DiagnosticLife ScienceLead InventorThomas KarikariDepartmentMed-PsychiatryAll Tech InnovatorsYijun ChenThomas K. KarikariNathan A. YatesDate Submitted2024-07-05
Novel Approach to Detect Skull or Other Bone Failure in Fixation06751Acoustic-emission skull clamp monitoring detects micro-cracking and slippage in real time, preventing neurosurgical bone injury.Technology TypeMedical DeviceTechnology SubtypeMonitoring Medical DeviceTherapeutic AreasNeuroscienceLead InventorAndrew BungerDepartmentCivil & Environmental EngineeringAll Tech InnovatorsAndrew P. BungerCharles Clemenes HagerWilliam HarbertTechnology Readiness Level4. Prototype testing and refinementDate Submitted2024-05-16
Novel Research Tool to Study TDP-43 Dysfunction06637CUTS-1 RNA biosensor flags TDP-43 dysfunction cells, enabling real-time disease tracking and targeted ALS/FTD/AD therapies.Technology TypeTherapeutic ModalityTechnology SubtypeGene Therapy - RNATherapeutic AreasNeuroscienceTherapeutic IndicationsAlzheimer's DiseaseLead InventorChristopher DonnellyDepartmentMed-NeurobiologyAll Tech InnovatorsChristopher James DonnellyDate Submitted2024-02-08CollectionsCell & Gene Therapy
Novel Use of Metformin to Treat Musculoskeletal Injury06416Metformin advances tendon healing by reducing fibrosis and inflammation, promoting angiogenesis for safer, cost-effective tendinopathy treatment.Technology TypeTherapeutic ModalityTechnology SubtypeDrug Delivery / FormulationTherapeutic AreasNeuroscienceMusculoskeletalLead InventorJames WangDepartmentMed-Orthopedic SurgeryAll Tech InnovatorsJames Huicong WangJianying ZhangTechnology Readiness Level3. Initial proof of concept, in-vivoDate Submitted2023-05-23CollectionsRegenerative Medicine
Novel Approach to Reverse Cerebral Cortex Decline06081Proteins linked to aging spine loss identified; 10 drugs may protect cognition, slowing dementia by preserving dendritic spines.Technology TypeTherapeutic ModalityTechnology SubtypeDrug Discovery - TargetTherapeutic AreasNeuroscienceTherapeutic IndicationsDementiaAlzheimer's DiseaseTagsAgingDrug RepurposingLead InventorRobert SweetDepartmentMed-PsychiatryAll Tech InnovatorsPeihao FanJoshua Michael KrivinkoMatthew Luke MacDonaldDate Submitted2022-06-30
A Genetically Engineered Mouse Model of Inflammatory Brain Injury05385CRISPR-edited mouse model replicates Aicardi-Goutières neuroinflammation for drug screening, target validation, and biomarker discovery.Technology TypeLife Science Research ToolTechnology SubtypeAnimal ModelTherapeutic AreasNeuroscienceLead InventorQingde WangDepartmentMed-SurgeryAll Tech InnovatorsXinfeng GuoQingde WangDate Submitted2020-05-28
AAV-Based Mitochondrial Gene Therapy: A Novel Approach to Slowing Neurodegeneration07363AAV-TIMs neurons: brain-wide delivery of TIM17/23/50 to restore mitochondrial import, slowing neurodegeneration across HD and beyond.Technology TypeTherapeutic ModalityTechnology SubtypeGene Therapy - AAVTherapeutic AreasNeuroscienceTherapeutic IndicationsParkinson's DiseaseHuntington's DiseaseAmyotrophic lateral sclerosis (ALS)TagsGeneticsRare diseasePlatform TechnologyLead InventorRobert FriedlanderDepartmentMed-Neurological SurgeryAll Tech InnovatorsSergei Victorovich BaranovDiane L. CarlisleRobert Max FriedlanderTechnology Readiness Level3. Initial proof of concept, in-vivoDate Submitted2025-10-06CollectionsCell & Gene Therapy
Novel Repair and Regeneration Therapy for Glaucoma07246AAV-Ina overexpression promotes retinal ganglion cell survival and axon regeneration, offering neuroprotection for glaucoma with regeneration potential.Technology TypeTherapeutic ModalityTherapeutic AreasNeuroscienceOphthalmologyTherapeutic IndicationsGlaucomaTagsDrug Discovery - TargetLife ScienceLead InventorKun Che ChangDepartmentMed-OphthalmologyAll Tech InnovatorsKun Che ChangChi-Yu ChenDate Submitted2025-07-11
Neuroprotective Peptide in Acute Ischemic Injury05442A brain-penetrant peptide (TAT-DP-2) disrupts Kv2.1 clusters to prevent delayed neuronal death after stroke.Technology TypeTherapeutic ModalityTechnology SubtypePeptideTherapeutic AreasNeuroscienceCardiovascularTherapeutic IndicationsStrokeOtherLead InventorElias AizenmanDepartmentMed-NeurobiologyAll Tech InnovatorsElias AizenmanJason Arnold JusticeAnthony John SchulienTechnology Readiness Level3. Initial proof of concept, in-vivoDate Submitted2020-07-09CollectionsCardiometabolic
Targeted Anodal Stimulation for Spinal Grey Matter: Precision Motor Recovery07374Targeted intra-spinal anodal stimulation activates motor neuron somata for precise hand and limb recovery, compatible with neuroprosthetics.Technology TypeTherapeutic ModalityTechnology SubtypeOther Therapeutic ModalityTherapeutic AreasNeuroscienceTherapeutic IndicationsMultiple Sclerosis (MS)TagsPlatform TechnologyLead InventorEvan RogersDepartmentMed-Neurological SurgeryAll Tech InnovatorsMarco CapogrossoEvan R. RogersTechnology Readiness Level3. Initial proof of concept, in-vivoDate Submitted2025-10-20
Integrated 3D Brain Organoids for Modeling the Blood-Brain Barrier and Neurological Disease Mechanisms06972Integrated 3D brain organoids recreate the blood-brain barrier for long-term neurodegenerative/viral research and safer drug screening.Technology TypeLife Science Research ToolTechnology SubtypeCell LineTherapeutic AreasNeuroscienceTherapeutic IndicationsParkinson's DiseaseAlzheimer's DiseaseLead InventorVelpandi AyyavooDepartmentGSPH-Infectious Diseases & MicrobiologyAll Tech InnovatorsVelpandi AyyavooRoberta Souza Dos ReisSathish SelvamDate Submitted2024-11-12
Transient-based click decoding for brain-computer interface cursor emulation05761Transient-based click decoding boosts iBCI cursor control with onset/offset neural transients, 10x accuracy gain, enabling robust click-and-drag.Technology TypeMedical DeviceTechnology SubtypeRehab or Assistive Medical DeviceTherapeutic AreasNeuroscienceMusculoskeletalTherapeutic IndicationsOtherLead InventorBrian DeklevaDepartmentMed-Physical Medicine & RehabilitationAll Tech InnovatorsJennifer Lynn CollingerBrian M. DeklevaTechnology Readiness Level3. Prototype developmentDate Submitted2021-07-14
HART: Health App Review Tool07091HART tailors health app recommendations for ADRD patients via four-domain assessment, guiding clinicians, patients, and caregivers.Technology TypeDigital HealthTechnology SubtypeHealthcare DeliveryTherapeutic AreasNeuroscienceTherapeutic IndicationsDementiaAlzheimer's DiseaseTagsClinical Decision SupportLife ScienceLead InventorJulie FaietaDepartmentSHRS-Rehab Sci & TechAll Tech InnovatorsYong Kyung ChoiJulie Marie FaietaHaomin HuDate Submitted2025-02-24
OptoTAU: A Novel Tool for Visualizing and Studying TAU06409OptoTAU enables light-controlled visualization of tau behavior in living cells, aiding discovery of modifiers to prevent tau-related dementia. (21 words)Technology TypeLife Science Research ToolTechnology SubtypeProteinTherapeutic AreasNeuroscienceTherapeutic IndicationsDementiaAlzheimer's DiseaseLead InventorAmantha ThathiahDepartmentMed-NeurobiologyAll Tech InnovatorsAmantha ThathiahXin ZhangDate Submitted2023-05-15CollectionsRare Diseases
4D Oxy-Wavelet MRI for Monitoring Mitochondrial Function062884D Oxy-Wavelet MRI noninvasively tracks mitochondrial function and oxygenation in live tissue with high-res, hypoxia-driven insights.Technology TypeMedical DeviceTechnology SubtypeDiagnostic ImagingTherapeutic AreasNeuroscienceEndocrinology and Metabolic DiseasesTherapeutic IndicationsOtherMitochondrial DiseaseTagsPediatricsRare diseaseDiagnostic ImagingLead InventorYijen WuDepartmentMed-PediatricsAll Tech InnovatorsAnthony G. ChristodoulouDevin Raine Everaldo CortesYijen WuDate Submitted2023-02-13CollectionsCardiometabolic
Novel Selective Kv7 Channel Modulators06017Selective novel chemotypes selectively modulate Kv7.2 channels, enabling safer treatments for epilepsy, tinnitus, channelopathies.Technology TypeTherapeutic ModalityTechnology SubtypeSmall MoleculeTherapeutic AreasNeuroscienceCardiovascularTagsLife ScienceLead InventorPeter WipfDepartmentChemistryAll Tech InnovatorsPeter WipfTechnology Readiness Level2. Initial proof of concept, in-vitroDate Submitted2022-05-02CollectionsCardiometabolic
Closed-Loop Neuromodulation for Intractable Epilepsy07408Closed-loop pulvinar DBS uses high-frequency burst biomarkers for personalized, real-time seizure control in refractory epilepsy.Technology TypeMedical DeviceTechnology SubtypeImplantable Medical DeviceTherapeutic AreasNeuroscienceTherapeutic IndicationsEpilepsyTagsAlgorithmPersonalized MedicineLead InventorJorge Gonzalez-MartinezDepartmentMed-Neurological SurgeryAll Tech InnovatorsDonald James CrammondJorge A. Gonzalez-MartinezSirisha Threpura NouduriTechnology Readiness Level3. Prototype developmentDate Submitted2025-11-11
Magneto-Vibrational Therapy for Phantom Limb Pain07142Non-invasive magnetically driven vibration therapy for phantom limb pain, compatible with prosthetic sockets; adjustable, patent-pending.Technology TypeMedical DeviceTechnology SubtypeRehab or Assistive Medical DeviceTherapeutic AreasNeuroscienceTherapeutic IndicationsPainTagsProstheticsLead InventorGoeran FiedlerDepartmentSHRS-Rehab Sci & TechAll Tech InnovatorsAiden ChinwallaGoeran FiedlerTechnology Readiness Level4. Prototype testing and refinementDate Submitted2025-04-07
iAChSnFR-BTX: A Novel Optical Probe to Monitor Neurotransmitter Release06606Novel optical probe iAChSnFR-BTX enables single-vesicle, real-time acetylcholine release imaging via irreversible toxin binding across species.Technology TypeLife Science Research ToolTherapeutic AreasNeuroscienceTherapeutic IndicationsAlzheimer's DiseaseLead InventorStephen MerineyDepartmentNeuroscienceAll Tech InnovatorsYomna BadawiStephen D. MerineyDate Submitted2024-01-09
Deep Brain Stimulation of the Pulvinar for the Treatment of Posterior Quadrant Epilepsy06581Pulvinar deep brain stimulation offers a subcortical, adjustable, potentially safer option for refractory posterior quadrant epilepsy.Technology TypeMedical DeviceTechnology SubtypeImplantable Medical DeviceTherapeutic AreasNeuroscienceTherapeutic IndicationsEpilepsyLead InventorElvira PirondiniDepartmentMed-Physical Medicine & RehabilitationAll Tech InnovatorsArianna DamianiJorge A. Gonzalez-MartinezElvira PirondiniDate Submitted2023-12-01
Novel Treatment for Retinitis Pigmentosa06383Pyrvinium targets NS LLPS to restore proteostasis, preserve retinal structure, and may treat retinitis pigmentosa and proteinopathies.Technology TypeTherapeutic ModalityTechnology SubtypeSmall MoleculeTherapeutic AreasNeuroscienceOphthalmologyTherapeutic IndicationsParkinson's DiseaseAlzheimer's DiseaseRetinitis pigmentosa (RP)TagsLife ScienceLead InventorBokai ZhuDepartmentMed-MedicineAll Tech InnovatorsYuanyuan ChenWilliam A. DionBokai ZhuDate Submitted2023-04-23
Novel Glycine Receptor Modulators for Analgesia04250Glycine receptor modulators (ZINC08) enhance analgesia without THC's psychoactivity, enabling opioid-sparing pain relief.Technology TypeTherapeutic ModalityTechnology SubtypeSmall MoleculeTherapeutic AreasNeuroscienceLead InventorYan XuDepartmentMed-Anesthesiology and Perioperative MedicineAll Tech InnovatorsPei TangMarta Megan WellsYan XuTechnology Readiness Level3. Initial proof of concept, in-vivoDate Submitted2017-05-17
Biosensors for the Detection of Brain Injury04031Antibody-aptamer biosensor detects tau in blood via electrochemical impedance, enabling rapid, portable TBI/ND biomarker diagnosis.Technology TypeEngineering TechnologyTechnology SubtypeSensorTherapeutic AreasNeuroscienceLead InventorPrashant KumtaDepartmentBioengineeringAll Tech InnovatorsRobert L. KormosPrashant N. KumtaDavid O. OkonkwoDate Submitted2016-09-23
Use of Deep Brain Stimulation to Treat Seizures06088Deep brain stimulation in motor thalamus offers seizure suppression without resection, via targeted neurostimulation and neuromodulation.Technology TypeMedical DeviceTechnology SubtypeImplantable Medical DeviceTherapeutic AreasNeuroscienceTherapeutic IndicationsEpilepsyTagsPediatricsBrain-computer interfaceLead InventorArianna DamianiDepartmentBioengineeringAll Tech InnovatorsMarco CapogrossoArianna DamianiJorge A. Gonzalez-MartinezDate Submitted2022-07-01
Whole Genome Sequencing Analytic Pipeline for Healthcare Associated Transmission05346EDS-HAT fuses whole-genome sequencing, ML, and EHRs to detect, map, and prevent hospital outbreaks in real time.Technology TypeDigital HealthTechnology SubtypeHealthcare DeliveryTherapeutic AreasNeuroscienceLead InventorXiangqun XieDepartmentPharm-Pharmaceutical ScienceAll Tech InnovatorsXiangqun XieYing XueDate Submitted2020-05-08
Skin Screw Electrodes for Recording and Physical Stability04146Skin screw electrodes securely anchor to skin with minimal discomfort, enabling stable EEG/EMG recording and wireless integration.Technology TypeMedical DeviceTechnology SubtypeSurgical Medical DeviceTherapeutic AreasNeuroscienceLead InventorMingui SunDepartmentMed-Neurological SurgeryAll Tech InnovatorsWenyan JiaRobert J. Sclabassi M.D., Ph.D.Mingui Sun Ph.D.Date Submitted2017-02-01
Bait Oligonucleotides to Prevent TDP-43 Associated Neurodegeneration06987Short RNA chaperones prevent and reverse TDP-43–related neurodegeneration by disaggregating harmful protein condensates.Technology TypeTherapeutic ModalityTechnology SubtypeGene Therapy - RNATherapeutic AreasNeuroscienceTherapeutic IndicationsParkinson's DiseaseAmyotrophic lateral sclerosis (ALS)Alzheimer's DiseaseLead InventorChristopher DonnellyDepartmentMed-NeurobiologyAll Tech InnovatorsChristopher James DonnellyJames ShorterTechnology Readiness Level5. Drug candidate createdDate Submitted2024-11-30CollectionsCell & Gene Therapy
Novel Approach to Modulate Neural Activity05653AM-HF neuromodulation induces asynchronous neural firing to enhance sensory feedback in prosthetics and reduce FES fatigue.Technology TypeMedical DeviceTechnology SubtypeRehab or Assistive Medical DeviceTherapeutic AreasNeuroscienceLead InventorBeatrice BarraDepartmentPhysical Medicine & RehabilitationAll Tech InnovatorsBeatrice BarraMarco CapogrossoLee Erik Bartholomew FisherDate Submitted2021-03-30
The Minister’s Cat – A Memory Game for Aphasia05639A memory-language game for aphasia using letters and prompts to boost speech, memory, and social interaction.Technology TypeDigital HealthTechnology SubtypeDigital TherapeuticTherapeutic AreasNeuroscienceTherapeutic IndicationsOtherTagsLife ScienceLead InventorWilliam EvansDepartmentSHRS-Commu Science & DisordersAll Tech InnovatorsMeguey BakerWilliam Streicher EvansKathryn HymesDate Submitted2021-03-16
A Neuromorphic Brain Decoding Method for Brain-Machine Interfaces05119Neuromorphic BMI decoding uses precise spike-time dynamics, outperforming rate coding to accurately infer intended hand movements.Technology TypeMedical DeviceTechnology SubtypeRehab or Assistive Medical DeviceTherapeutic AreasNeuroscienceTherapeutic IndicationsOtherTagsHuman performanceLead InventorBenjamin BenosmanDepartmentMed-OphthalmologyAll Tech InnovatorsHimanshu AkolkarBenjamin BenosmanAndrew B. SchwartzDate Submitted2019-09-24
