Complex Coacervate for Controlled Release
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The gel allows for controlled release of treatment for DED, requiring less applications, and has the potential to improve regimen compliance, allowing for direct treatment of the underlying cause of DED. Integrating these peptides into a coacervate gel leads to controlled, sustained release of medication into the eye and could provide a novel treatment approach for DED and other eye diseases. In all three studies the eye surface was improved back to baseline, whereas the control groups demonstrated continued damage to the eye surface.
Thermoresponsive Hydrogel Containing Polymer Microparticles for Controlled Drug Delivery to the Ear
03810
They provide a consistent, controlled release of antibiotics over 14 days. Furthermore, the easily removable, non-degradable hydrogel facilitates post-treatment clearance, distinguishing this system from more invasive or less controlled alternatives. - Controlled antibiotic release system.
Controlled drug release scaffolds. What differentiates this technology is its capacity to deliver localized, controlled therapy while minimizing systemic exposure and associated risks. This system employs bioerodible polymer microparticles made from PLGA to enable the local, sustained release of a BMP type I receptor inhibitor such as dorsomorphin.