Complex Coacervate for Controlled Release
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Thermoresponsive Hydrogel Containing Polymer Microparticles for Controlled Drug Delivery to the Ear
03810
They provide a consistent, controlled release of antibiotics over 14 days. Furthermore, the easily removable, non-degradable hydrogel facilitates post-treatment clearance, distinguishing this system from more invasive or less controlled alternatives. - Controlled antibiotic release system.
Controlled release of ciprofloxacin and ceftriaxone from a single ototopical administration of antibiotic-loaded polymer microspheres and thermoresponsive gel. Modification of the polymer microparticle could regulate the timeframe over which a therapeutic agent is released. The microparticle can be tailored to control slow release of the therapeutic agent.
- Vascular graft scaffolds. - Myocardial repair scaffolds. - Cartilage tissue scaffolds. - Drug delivery platforms. Advantages. - Controlled and consistent degradation via surface erosion that aligns with tissue regeneration rates.
- 3Therapeutic Modality
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- 3Drug Delivery / Formulation
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- 1Ophthalmology
- 1Otolaryngology
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- 1Conjunctivitis
- 1Glaucoma
- 1Keratitis
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- 8Platform Technology
- 5Biomaterial
- 4Tissue engineering
- 3Drug delivery
- 3Polymer
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- 2Morgan Dileo
- 1Shilpa Sant
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- 2Med-Ophthalmology
- 1Department of Pharmaceutical Sciences
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- 2Joel Steven Schuman
- 2Morgan Virginia Dileo
- 2Steven R. Little
- 1Liza Anna Bruk
- 1Shilpa Sant
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