Tissue engineering

46 results

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Biomimetic 3D-Printed Platform for Personalized Mechanotransduction and Disease Modeling in Glaucoma

07146

Biomimetic 3D-printed glaucoma model enabling patient-specific mechanotransduction study, genomic changes, and drug screening.

Technology Type: Life Science Research Tool
Therapeutic Areas: Ophthalmology
Therapeutic Indications: Glaucoma
Tags: Tissue engineering
Biomaterial
Platform Technology
Lead Inventor: Jonathan Vande Geest
Department: Bioengineering
All Tech Innovators: Ian P. Conner
Susana Isabel Morgado Mendes Antunes da>VF
Remi Jessica Shittu
Technology Readiness Level: 3. Prototype development
Date Submitted: 2025-04-10

Microparticle-Based Regulatory T Cell Recruitment for Muscle Regeneration

07174

Recruit Treg-evoked immune modulation via PLGA/PEG microparticles releasing CCL22 to enhance acute muscle regeneration.

Technology Type: Therapeutic Modality
Technology Subtype: Cell Therapy - T Cell
Therapeutic Areas: Musculoskeletal
Tags: Tissue engineering
Regenerative medicine
Sports medicine
Lead Inventor: Matthew Borrelli
Department: Chem/Petroleum Engineering
All Tech Innovators: Matthew Andrew Borrelli
Steven R. Little
Heth Turnquist
Technology Readiness Level: 4. Pre-clinical development
Date Submitted: 2025-05-05
Collections: Cell & Gene Therapy
Regenerative Medicine

Innovative 3D Bioprinting for Primary and iPSC-Derived Organoids

06820

3D bioprinting platform creates functional primary and iPSC-derived organoids in alginate-methylcellulose hydrogel for personalized tissue applications.

Technology Type: Engineering Technology
Technology Subtype: Other Engineering Technology
Therapeutic Areas: Other
Tags: Tissue engineering
Regenerative medicine
Lead Inventor: Miranda Poklar
Department: Chem/Petroleum Engineering
All Tech Innovators: Ipsita Banerjee
Yong Fan
Prashant N. Kumta
Date Submitted: 2024-07-24

Novel Patient-Derived Assembloid Model Accelerates Immunotherapy Development for Difficult-to-Treat Cancers

06922

Patient-derived assembloid with tumor-immune co-cultures accelerates immunotherapy/vaccine development for hard-to-treat head and neck cancers.

Technology Type: Life Science Research Tool
Technology Subtype: Cell Line
Therapeutic Areas: Immunology
Oncology
Therapeutic Indications: Solid tumor
Tags: Tissue engineering
Immuno-oncology
Platform Technology
Lead Inventor: Riyue Bao
Department: Med-Medicine
All Tech Innovators: Riyue Bao
Jason J. Luke
Technology Readiness Level: 3. Prototype development
Date Submitted: 2024-10-16

Novel Maxillo-Mandibular Measurement Tool

05982

A handheld, disposable/reusable tool accurately measures pediatric alveolar overjet for craniofacial assessment and surgical planning.

Technology Type: Medical Device
Technology Subtype: Other Medical Device
Therapeutic Areas: Surgery
Dental
Tags: Tissue engineering
Pediatrics
Lead Inventor: Jesse Goldstein
Department: Med-Plastic Surgery
All Tech Innovators: Justin Beiriger
Jesse A. Goldstein
Technology Readiness Level: 3. Prototype development
Date Submitted: 2022-03-10

Novel Approach to Treatment of Osteoarthritis

05840

Enhancing estrogen receptor-α in cartilage reverses osteoarthritis damage; potential ERα-targeted therapies emerge with RAD001 and Urolithin A.

Technology Type: Therapeutic Modality
Technology Subtype: Drug Delivery / Formulation
Therapeutic Areas: Musculoskeletal
Tags: Tissue engineering
Aging
Regenerative medicine
Lead Inventor: Hang Lin
Department: Med-Orthopedic Surgery
All Tech Innovators: Hang Lin
Ning Wang
Technology Readiness Level: 3. Initial proof of concept, in-vivo
Date Submitted: 2021-10-13

Scaffold-Free Nerve Conduit Comprising Cells, Secretome, and Endogenous Aligned Extracellular Matrix

05228

Scaffold-free, autologous dental pulp stem cell conduit uses aligned extracellular matrix and secretome to accelerate facial nerve repair.

Technology Type: Medical Device
Technology Subtype: Rehab or Assistive Medical Device
Therapeutic Areas: Rehabilitation/Mobility
Neuroscience
Tags: Tissue engineering
Biomaterial
Regenerative medicine
Lead Inventor: Fatima Syed
Department: Dent Med-Oral and Craniofacial Sciences
All Tech Innovators: Fatima N. Syed
Date Submitted: 2020-01-21

Nanoparticle Dopants for Conducting Polymers

04941

Nanoparticle-doped PEDOT lowers impedance, boosts charge injection and drug loading for improved neural interfaces.

Technology Type: Medical Device
Technology Subtype: Implantable Medical Device
Therapeutic Areas: Cardiovascular
Neuroscience
Tags: Tissue engineering
Biomaterial
Coating
Lead Inventor: Xinyan Cui
Department: Bioengineering
All Tech Innovators: Xinyan Cui
Kevin M. Woeppel
Date Submitted: 2019-04-03
Collections: Cardiometabolic

Ovarian ECM Derivatives for Women's Health Applications

04945

Bioengineered ovarian ECM hydrogel enables rapid follicle delivery to restore fertility and endocrine function after chemotherapy.

Technology Type: Engineering Technology
Technology Subtype: Industrial Biotech
Therapeutic Areas: Reproductive Health
Tags: Tissue engineering
Biomaterial
Regenerative medicine
Lead Inventor: Michael Buckenmeyer
Department: Bioengineering
All Tech Innovators: Bryan Nicklaus Brown
Michael Joseph Buckenmeyer
Kyle E. Orwig
Date Submitted: 2019-04-06
Collections: Women's & Reproductive Health

Automated Dip-Coating Platform for Fabricating Resorbable Nerve Guide Constructs

04805

Automated dip-coating platform creates multi-layer, biodegradable nerve guides with embedded particles for reproducible peripheral nerve repair.

Technology Type: Life Science Research Tool
Therapeutic Areas: Neuroscience
Tags: Tissue engineering
Biomaterial
Regenerative medicine
Lead Inventor: Benjamin Schilling
Department: Bioengineering
All Tech Innovators: Kacey Gribbin Marra
Alexander James Repko
Benjamin Schilling
Technology Readiness Level: 5. Advanced prototype validation
Date Submitted: 2018-11-06

Novel Processing Method and Apparatus for Micro-Structured Rope-Like Material

04694

Novel mandrel-less electrospinning creates infinite, customizable-diameter, rope-like microfibers for tendon, nerve, ligament regeneration.

Technology Type: Medical Device
Technology Subtype: Surgical Medical Device
Therapeutic Areas: Musculoskeletal
Tags: Tissue engineering
Polymer
Lead Inventor: Antonio DAmore
Department: Med-Surgery
All Tech Innovators: Antonio DAmore
Daniel T. McKeel
William R. Wagner PhD
Date Submitted: 2018-07-30
Collections: Regenerative Medicine

Scaffold-Free Cell Sheet for Nerve Repair

04482

Scaffold-free dental stem cell sheets deliver neurotrophic factors locally to accelerate nerve regeneration and motor recovery.

Technology Type: Medical Device
Technology Subtype: Implantable Medical Device
Therapeutic Areas: Neuroscience
Tags: Tissue engineering
Regenerative medicine
Surgery
Lead Inventor: Fatima Syed
Department: Dent Med-Oral and Craniofacial Sciences
All Tech Innovators: Fatima N. Syed
Date Submitted: 2018-01-12
Collections: Regenerative Medicine

Magnetic Delivery System and Hydrogel Fixative for Therapeutic Cells

04531

Magnetic-assisted hydrogel fixation delivers adipose-derived stem cells to target sites, enabling minimally invasive, localized therapy.

Technology Type: Therapeutic Modality
Technology Subtype: Drug Delivery / Formulation
Therapeutic Areas: Other
Tags: Tissue engineering
Biomaterial
Regenerative medicine
Lead Inventor: David Vorp
Department: Bioengineering
All Tech Innovators: Yogev Baruch
Kory James Blose
Timothy K. Chung
Technology Readiness Level: 2. Initial proof of concept, in-vitro
Date Submitted: 2018-03-05

Regenerative Ligament Repair Therapy

04487

Soluble ACL/PCL extracellular matrix extracts promote stem cell proliferation and tenogenic differentiation, enabling regenerative ligament therapies.

Technology Type: Medical Device
Technology Subtype: Implantable Medical Device
Therapeutic Areas: Musculoskeletal
Tags: Tissue engineering
Biomaterial
Regenerative medicine
Lead Inventor: Riccardo Gottardi
All Tech Innovators: Riccardo Luca Gottardi
Shinsuke Kihara
Benjamin Burke Rothrauff
Date Submitted: 2018-01-17

Novel Biomimetic Rotated Plywood Motifs as Scaffolds for Bone Tissue Engineering

03778

Biomimetic rotated plywood bone scaffolds via binder-jet 3D printing; data-driven, multi-material, enhanced strength, tailored implants.

Technology Type: Medical Device
Technology Subtype: Implantable Medical Device
Therapeutic Areas: Musculoskeletal
Tags: Tissue engineering
Regenerative medicine
Surgery
Lead Inventor: Prashant Kumta
Department: Bioengineering
All Tech Innovators: Prashant N. Kumta
Gary Zhengbo Yu
Date Submitted: 2015-11-27

Self-Assembled Coatings for Magnesium Implants

04203

Self-assembling anticorrosive organosilane coating slows magnesium implant degradation, enabling drug delivery and improved biocompatibility.

Technology Type: Therapeutic Modality
Technology Subtype: Drug Delivery / Formulation
Therapeutic Areas: Musculoskeletal
Dental
Tags: Tissue engineering
Biomaterial
Coating
Lead Inventor: Elia Beniash
Department: Dent Med-Oral and Craniofacial Sciences
All Tech Innovators: Elia Beniash
Avinash Jagannath Patil
Technology Readiness Level: 3. Initial proof of concept, in-vivo
Date Submitted: 2017-04-04

Nitrix: A Biomaterial Bandage for Closing Chronic Wounds

04182

Nitrix: a low-cost ECM biomaterial bandage that boosts antioxidant, anti-inflammatory, and angiogenic healing for chronic wounds.

Technology Type: Engineering Technology
Technology Subtype: Industrial Biotech
Therapeutic Areas: Intensive Care
Tags: Tissue engineering
Biomaterial
Regenerative medicine
Lead Inventor: Samuel LoPresti
Department: Bioengineering
All Tech Innovators: Bryan Nicklaus Brown
Samuel Traxler LoPresti
Date Submitted: 2017-03-06
Collections: Regenerative Medicine

A Biodegradable, Porous, Thermally Responsive Injectable Hydrogel as Soft Tissue Defect Filler

04040

Biodegradable, injectable hydrogel with in situ gelation, porosity, ECM cues, and rapid tissue regeneration for soft-tissue repair.

Technology Type: Medical Device
Technology Subtype: Implantable Medical Device
Tags: Tissue engineering
Biomaterial
Regenerative medicine
Lead Inventor: William Wagner
Department: Bioengineering
All Tech Innovators: Stephen Francis Badylak DVM, PhD, MD
Hong Bin Jiang
Hideyoshi Sato
Date Submitted: 2016-10-04
Collections: Regenerative Medicine

A Shear-thinning Hydrogel That Extends In Vivo Bioactivity of Therapeutic Proteins

03988

Injectable, shear-thinning hydrogel using silicate nanoplatelets and heparin enables rapid, tunable, Bioactive protein delivery and biodegrades in 8 weeks.

Technology Type: Therapeutic Modality
Technology Subtype: Drug Delivery / Formulation
Tags: Tissue engineering
Biomaterial
Regenerative medicine
Lead Inventor: Yadong Wang
Department: Bioengineering
All Tech Innovators: Xiaochu Ding
Jin Gao
Yadong Wang
Date Submitted: 2016-07-07
Collections: Regenerative Medicine

Regeneration of Epiphyseal Growth Plate

03828

Hydrogel-MSC scaffolds with cytokines and microparticles direct chondrogenesis, regenerating growth plate tissue to prevent deformities in children.

Technology Type: Medical Device
Technology Subtype: Implantable Medical Device
Therapeutic Areas: Dental
Tags: Tissue engineering
Regenerative medicine
Life Science
Lead Inventor: Juan Taboas
Department: Dent Med-Oral and Craniofacial Sciences
All Tech Innovators: Jingming Chen
Juan M. Taboas
Date Submitted: 2016-02-10

Stem Cell-Based Technologies for Avian Skeletal Tissue Engineering and Regeneration

03360

Light-activated, 3D-printed avian stem cell scaffolds enable precise bone/cartilage repair with antibacterial protection.

Technology Type: Therapeutic Modality
Technology Subtype: Cell Therapy - Stem Cell
Therapeutic Areas: Musculoskeletal
Tags: Tissue engineering
Regenerative medicine
Lead Inventor: Rocky Tuan
Department: Med-Orthopedic Surgery
All Tech Innovators: Rocky Sung Chi Tuan
Date Submitted: 2014-07-07
Collections: Cell & Gene Therapy
Regenerative Medicine

Method of Making Trabecular Bone in vitro

03691

Efficient in vitro trabecular bone generation from modified mesenchymal stem cells enables implants, osteoporosis treatment, and dental grafts.

Technology Type: Engineering Technology
Technology Subtype: Industrial Biotech
Therapeutic Areas: Musculoskeletal
Tags: Tissue engineering
Aging
Biomaterial
Lead Inventor: Harry Blair
Department: Med-Pathology
All Tech Innovators: Harry Colbert Blair
Quitterie Larrouture
Deborah J. Nelson
Date Submitted: 2015-07-31
Collections: Women's & Reproductive Health

Biomimetic Fibrous Hydrogel Scaffolds Promote Biomineralization

03610

Injectable biomimetic fibrous hydrogel scaffolds self-assemble electrostatically to guide bone-like mineralization and drug delivery.

Technology Type: Medical Device
Technology Subtype: Implantable Medical Device
Therapeutic Areas: Musculoskeletal
Tags: Tissue engineering
Biomaterial
Lead Inventor: Shilpa Sant
Department: Department of Pharmaceutical Sciences
All Tech Innovators: Shilpa Sant
Date Submitted: 2015-05-11

Resorbable Magnesium Hardware for Bone Fractures

03562

Biodegradable magnesium bone fixation hardware matches strength, promotes bone growth, and eliminates removal surgeries through gradual resorption.

Technology Type: Medical Device
Technology Subtype: Surgical Medical Device
Therapeutic Areas: Musculoskeletal
Tags: Tissue engineering
Biomaterial
Regenerative medicine
Lead Inventor: Prashant Kumta
Department: Bioengineering
All Tech Innovators: Da-Tren Chou
Vijay S. Gorantla
Dae Ho Hong
Date Submitted: 2015-03-24
Collections: Regenerative Medicine

Self-Assembled Coatings for Magnesium Implants

03377

Self-assembled anticorrosive organosilane coatings slow magnesium implant degradation, enabling drug delivery and improved biocompatibility.

Technology Type: Medical Device
Technology Subtype: Surgical Medical Device
Therapeutic Areas: Musculoskeletal
Therapeutic Indications: Other
Tags: Tissue engineering
Biomaterial
Coating
Lead Inventor: Elia Beniash
Department: Dent Med-Oral and Craniofacial Sciences
All Tech Innovators: Elia Beniash
Date Submitted: 2014-08-11

Controlled Release Microparticle Platform for Localized Prevention of Tissue Calcification and Ossification

03248

PLGA microparticles deliver BMP receptor inhibitor locally to prevent tissue calcification with sustained, customizable release.

Technology Type: Therapeutic Modality
Technology Subtype: Drug Delivery / Formulation
Therapeutic Areas: Musculoskeletal
Tags: Tissue engineering
Regenerative medicine
Sports medicine
Lead Inventor: Riccardo Gottardi
All Tech Innovators: Peter Alexander
Patrick A. Bianconi
Riccardo Luca Gottardi
Date Submitted: 2014-02-17

Hybrid Additive Manufacturing and Electrospinning for Fabricating Vascularized Biodegradable Tissue Scaffolds

03187

Hybrid 3D printing and electrospinning create biodegradable, porous, vascularized tissue scaffolds with programmable microchannels.

Technology Type: Medical Device
Technology Subtype: Implantable Medical Device
Tags: Tissue engineering
Regenerative medicine
Lead Inventor: Yadong Wang
Department: Bioengineering
All Tech Innovators: James Henry Clampffer III
Eric M. Jeffries
Yadong Wang
Date Submitted: 2013-12-04

Superelastic, Bioabsorbable Endovascular Devices

03179

Superelastic, mostly-biodegradable endovascular scaffold that self-expands with temperature, offers temporary support, then safely resorbs.

Technology Type: Medical Device
Technology Subtype: Implantable Medical Device
Therapeutic Areas: Cardiovascular
Tags: Tissue engineering
Biomaterial
Lead Inventor: Young Chun
Department: Industrial Engineering
All Tech Innovators: Youngjae Jae Chun
Xinzhu Gu
William R. Wagner PhD
Date Submitted: 2013-11-22
Collections: Regenerative Medicine
Cardiometabolic

Corrosion-Resistant, Bioactive Coatings for Magnesium -Based Medical Devices

03014

Bioactive PEM coatings yield corrosion resistance, improved biocompatibility, and controlled biomolecule delivery for magnesium-based implants.

Technology Type: Medical Device
Technology Subtype: Implantable Medical Device
Therapeutic Areas: Dental
Musculoskeletal
Tags: Tissue engineering
Biomaterial
Coating
Lead Inventor: Prashant Kumta
Department: Bioengineering
All Tech Innovators: Prashant N. Kumta
Sangeetha Kunjukunju
Boeun Lee
Date Submitted: 2013-04-01

New Biometric Coating for Neural Implants Improves Outcomes

03008

Neural implants gain lasting accuracy via L1 coating, boosting neuron adherence, reducing glial response, and sustaining high-quality signals.

Technology Type: Medical Device
Technology Subtype: Surgical Medical Device
Therapeutic Areas: Neuroscience
Therapeutic Indications: Parkinson's Disease
Epilepsy
Tags: Tissue engineering
Coating
Regenerative medicine
Lead Inventor: Xinyan Cui
Department: Bioengineering
All Tech Innovators: Erdrin Azemi
Xinyan Cui
Carl F. Lagenaur
Date Submitted: 2013-03-28

Degradable Osteosensor: Novel Degradable CNT-based Impedimetric Biosensors for Bone Marker Detection

03000

Degradable CNT-based impedimetric sensor detects bone resorption markers; biodegradable, home-use osteosense enables in vivo monitoring.

Technology Type: Medical Device
Technology Subtype: Implantable Medical Device
Therapeutic Areas: Immunology
Musculoskeletal
Therapeutic Indications: Rheumatoid arthritis
Osteoporosis
Bone metabolism
Tags: Tissue engineering
Aging
Biomaterial
Lead Inventor: Prashant Kumta
Department: Bioengineering
All Tech Innovators: Prashant N. Kumta
Mitali S. Patil
Madhumati Ramanathan
Technology Readiness Level: 3. Prototype development
Date Submitted: 2013-03-04
Collections: Women's & Reproductive Health

Advanced Electrospinning for Regenerative Biomaterials

02919

Novel electrospun PGS biomaterials blends yield suturable, tough, elastic vascular grafts, nerve guides, and regenerative scaffolds.

Technology Type: Engineering Technology
Technology Subtype: Material Science
Tags: Tissue engineering
Biomaterial
Regenerative medicine
Lead Inventor: Eric Jeffries
Department: Bioengineering
All Tech Innovators: Eric M. Jeffries
Yadong Wang
Technology Readiness Level: 4. Prototype testing and refinement
Date Submitted: 2012-10-23

Bio-Inspired Nanocomposites for Advanced Bone and Tissue Regeneration

02778

Bio-inspired bone/dentin nanocomposites using multiphosphorylated peptides for integrated organic-inorganic regeneration and osteogenesis.

Technology Type: Therapeutic Modality
Technology Subtype: Peptide
Therapeutic Areas: Intensive Care
Musculoskeletal
Therapeutic Indications: Trauma
Osteogenesis Imperfecta
Bone metabolism
Tags: Tissue engineering
Biomaterial
Regenerative medicine
Lead Inventor: Elia Beniash
Department: Dent Med-Oral and Craniofacial Sciences
All Tech Innovators: Elia Beniash
Charles S. Sfeir
Technology Readiness Level: 5. Drug candidate created
Date Submitted: 2012-05-25
Collections: Regenerative Medicine

Revolutionary Perfusion Solution for Extended Organ Preservation and Improved Transplant Outcomes

02777

Oxygenated acellular hemoglobin perfusate preserves organs longer at sub‑normothermia, improving transplant viability and function.

Technology Type: Medical Device
Technology Subtype: Surgical Medical Device
Tags: Tissue engineering
Surgery
Lead Inventor: Paulo Fontes
Department: Med-Surgery
All Tech Innovators: Paulo Artur Chaves Fontes
Date Submitted: 2012-05-24

Bioreactor for Physiologic Loading of Epithelialized Hollow Organs

02411

A bioreactor cyclically distends epithelialized hollow organs, delivering luminal pressure and controlled flow to support multi-tissue growth.

Technology Type: Life Science Research Tool
Technology Subtype: Cell Line
Tags: Tissue engineering
Lead Inventor: Thomas Gilbert
Department: Bioengineering
All Tech Innovators: Thomas W. Gilbert
Mark Juhas
Nathaniel Thomas Remlinger
Date Submitted: 2011-02-21

Low Passage Mesenchymal Stem Cell Cell Bank from Cadaveric Vertebral Bodies

02247

Cadaver vertebra-derived MSC bank enables rapid, large-scale expansion in bioreactors, reducing chromosomal risks and passage.

Technology Type: Life Science Research Tool
Technology Subtype: Cell Line
Therapeutic Areas: Immunology
Tags: Tissue engineering
Regenerative medicine
Lead Inventor: Albert Donnenberg
Department: Med-Medicine
All Tech Innovators: Albert D. Donnenberg
Ludovic Zimmerlin
Date Submitted: 2010-06-09

Biodegradable Electrospun Scaffolds for Enhanced Tissue Repair and Cellular Infiltration

02170

Biodegradable wet-electrospun scaffolds enhance tissue repair with bioactive, integrated fibers for superior cellular infiltration and mechanics.

Technology Type: Medical Device
Technology Subtype: Implantable Medical Device
Tags: Tissue engineering
Biomaterial
Polymer
Lead Inventor: Yi Hong
All Tech Innovators: Nicholas J. Amoroso
Kazuro Lee Fujimoto
Ryotaro Hashizume
Date Submitted: 2010-03-22
Collections: Regenerative Medicine

A Novel Biohybrid Composite Scaffold

02205

Elastic biohybrid scaffold combining ECM gel and electrospun elastomer fibers for improved integration and support.

Technology Type: Medical Device
Technology Subtype: Implantable Medical Device
Tags: Tissue engineering
Biomaterial
Lead Inventor: Yi Hong
All Tech Innovators: Stephen Francis Badylak DVM, PhD, MD
Ryotaro Hashizume
Yi Hong
Date Submitted: 2010-04-27
Collections: Regenerative Medicine

Acellular Central Nervous System (Spinal Cord)-Derived Product for Tissue Engineering and Regenerative Therapies

01915

Acellular porcine spinal cord scaffold supports neuronal growth; injectable, lyophilizable CNS biomaterial for regenerative therapy.

Technology Type: Therapeutic Modality
Technology Subtype: Protein
Therapeutic Areas: Neuroscience
Tags: Tissue engineering
Biomaterial
Lead Inventor: Alan Boruch
Department: Med-Pharmacology and Chemical Biology
All Tech Innovators: Alan V. Boruch
Date Submitted: 2009-02-05

Novel Nanostructured Smart Injectable Bone Cements for Bone Regeneration

01918

Smart injectable calcium phosphate bone cement carries proteins, DNA, cells, and drugs; enables rapid, porous, 3D-printed, regenerative bone repair.

Technology Type: Medical Device
Technology Subtype: Implantable Medical Device
Therapeutic Areas: Musculoskeletal
Therapeutic Indications: Osteoporosis
Bone metabolism
Tags: Tissue engineering
Aging
Biomaterial
Lead Inventor: Prashant Kumta
Department: Bioengineering
All Tech Innovators: Prashant N. Kumta
Abhijit Roy
Charles S. Sfeir
Date Submitted: 2009-02-13
Collections: Women's & Reproductive Health

Novel Peptides for Tissue Reconstruction

01877

Synthetic peptides recruit patient progenitor cells to injury sites, enabling targeted tissue healing without stem cell harvesting.

Technology Type: Therapeutic Modality
Technology Subtype: Peptide
Tags: Tissue engineering
Biomaterial
Regenerative medicine
Lead Inventor: Stephen Badylak
Department: Med-Surgery
All Tech Innovators: Stephen Francis Badylak DVM, PhD, MD
Stephen Tottey
Date Submitted: 2008-11-26
Collections: Regenerative Medicine

Thermoresponsive, Biodegradable, Elastomeric Material

01315

Biodegradable, thermoresponsive hydrogel that is injectable, ultra-flexible, and shapes with temperature for tissue engineering and drug delivery.

Technology Type: Medical Device
Technology Subtype: Implantable Medical Device
Tags: Tissue engineering
Biomaterial
Regenerative medicine
Lead Inventor: William Wagner
Department: Bioengineering
All Tech Innovators: Jianjun Guan
William R. Wagner PhD
Date Submitted: 2006-09-14
Collections: Regenerative Medicine

Biodegradable Polyester Urethane Urea Cardiac Patch

01261

Biodegradable elastomeric PEUU cardiac patch grows with patient, reduces remodeling, and supports host tissue integration and recovery.

Technology Type: Medical Device
Technology Subtype: Therapeutic Medical Device
Therapeutic Areas: Cardiovascular
Tags: Tissue engineering
Biomaterial
Lead Inventor: William Wagner
Department: Bioengineering
All Tech Innovators: Kazuro Lee Fujimoto
Jianjun Guan
Bradley B. Keller
Date Submitted: 2006-05-04
Collections: Regenerative Medicine
Cardiometabolic

Biohybrid Elastomeric Scaffolds for Wound Healing and Tissue Regeneration

01174

Biohybrid elastomeric scaffolds merge synthetic and biological polymers to enhance wound healing and tissue regeneration.

Technology Type: Medical Device
Technology Subtype: Implantable Medical Device
Tags: Tissue engineering
Biomaterial
Regenerative medicine
Lead Inventor: William Wagner
Department: Bioengineering
All Tech Innovators: Stephen Francis Badylak DVM, PhD, MD
Donald O. Freytes MSBME
Thomas W. Gilbert
Date Submitted: 2005-11-16
Collections: Regenerative Medicine

Cellular Biobandage: A ‘Smart’ Gel for Wound Healing

01062

Smart, antimicrobial, fast-curing gel with mesenchymal cells to rapidly seal wounds, inhibit inflammation, and boost healing.

Technology Type: Therapeutic Modality
Technology Subtype: Drug Delivery / Formulation
Tags: Tissue engineering
Polymer
Regenerative medicine
Lead Inventor: Eric Beckman
Department: Chem/Petroleum Engineering
All Tech Innovators: Stephen Francis Badylak DVM, PhD, MD
Eric J. Beckman
Donald O. Freytes MSBME
Technology Readiness Level: 3. Initial proof of concept, in-vivo
Date Submitted: 2005-03-07
Collections: Regenerative Medicine

Vacuum Seeding Rotational Device

00985

Rotational vacuum seeding speeds uniform, rapid cellular grafting on tubular scaffolds for fast, shelf-stable, personalized tissue engineering.

Technology Type: Medical Device
Technology Subtype: Therapeutic Medical Device
Therapeutic Areas: Cardiovascular
Tags: Tissue engineering
Regenerative medicine
Plastic Surgery
Lead Inventor
All Tech Innovators: Alejandro Nieponice
Lorenzo Soletti
David A. Vorp Ph.D.
Date Submitted: 2004-08-19
Collections: Cardiometabolic