EVOLV-Rx: Automated Decision Support for Eliminating Low-Value Clinical Practices07182Automated, cross-source detection of low-value prescribing to reduce harm; scalable decision support for providers, payers, and hospitals.Technology TypeDigital HealthTechnology SubtypeHealthcare DataTherapeutic AreasEndocrinology and Metabolic DiseasesRespiratoryTherapeutic IndicationsDiabetesChronic Obstructive Pulmonary Disease (COPD)TagsAgingAlgorithmPersonalized MedicineLead InventorThomas RadomskiDepartmentMed-MedicineAll Tech InnovatorsThomas R. RadomskiTechnology Readiness Level4. Prototype testing and refinementDate Submitted2025-05-12CollectionsCardiometabolic
Comprehensive Training Program for Addressing Adolescent Substance Use06890A primary-care–oriented training program for health professionals addressing adolescent substance use, SUD impacts, ethics, and referrals.Technology TypeOtherTagsEducation TechnologyLead InventorHeather SantaDepartmentMed-MedicineAll Tech InnovatorsHeather Marie SantaDate Submitted2024-09-21
Skill-Building on Motivational Interviewing and POLAR*S06858Innovative MI training for primary care HCPs using POLAR*S to collaboratively support patient substance-use behavior change.Technology TypeOtherTagsEducation TechnologyLead InventorHeather SantaDepartmentMed-MedicineAll Tech InnovatorsHeather Marie SantaDate Submitted2024-08-29
My Decision/Mi Decisión: Evidence-Based Digital Decision Aid for Informed Permanent Contraception Choices06841Evidence-based web decision aid improves knowledge and reduces decisional conflict for permanent contraception choices.Technology TypeDigital HealthTechnology SubtypeClinical Decision SupportTherapeutic AreasReproductive HealthTagsWomen's HealthLead InventorSonya BorreroDepartmentMed-MedicineAll Tech InnovatorsSonya B. BorreroDate Submitted2024-08-19CollectionsWomen's & Reproductive Health
AI-Powered Single-Cell Analysis from Standard H&E Slides for Personalized Cancer Therapy Prediction06923AI-driven single-cell typing from standard H&E slides enables personalized cancer therapy predictions, increasing accessibility and speed.Technology TypeLife Science Research ToolTechnology SubtypeBioinformaticsTherapeutic AreasOncologyTherapeutic IndicationsHepatocellular carcinoma (HCC)Solid tumorTagsArtificial intelligence (AI)BiomarkerAlgorithmLead InventorRiyue BaoDepartmentMed-MedicineAll Tech InnovatorsRiyue BaoJason J. LukeTechnology Readiness Level4. Prototype testing and refinementDate Submitted2024-10-16CollectionsHealthcare AI
Educating Clinicians on Injection Drug Use06887Educational tool trains clinicians in IDU SBIRT to discuss risks, reduce stigma, and enable harm-reduction care.Technology TypeOtherTagsEducation TechnologyLead InventorHeather SantaDepartmentMed-MedicineAll Tech InnovatorsHeather Marie SantaDate Submitted2024-09-20
Bacteriophage Cocktail to Treat Achromobacter06380Five phages form a cocktail to broaden Achromobacter targeting, offering personalized, antibiotic-sparing therapy potential.Technology TypeTherapeutic ModalityTechnology SubtypeBacteriophageTherapeutic AreasRespiratoryInfectious DiseaseTherapeutic IndicationsOtherLead InventorDaria Van TyneDepartmentMed-MedicineAll Tech InnovatorsGhady HaidarDaria N. Van TyneTechnology Readiness Level2. Initial proof of concept, in-vitroDate Submitted2023-04-20
Intestinal Microbiome Modulation to Enhance Anti-Tumor Immunity05545Gut microbiome–driven FMT plus anti-PD-1 boosts anti-tumor immunity in PD-1–refractory melanoma patients; tolerable, durable responses.Technology TypeTherapeutic ModalityTechnology SubtypeOther Therapeutic ModalityTherapeutic AreasOncologyTherapeutic IndicationsMelanomaLead InventorDiwakar DavarDepartmentMed-MedicineAll Tech InnovatorsDiwakar DavarAmiran DzutsevGiorgio TrinchieriDate Submitted2020-11-01
AI-Driven ECG Analysis for Rapid Identification of High-Risk Pulmonary Embolism07187AI-driven 12-lead ECG detects high-risk pulmonary embolism with 0.90 AUC, enabling rapid triage and earlier intervention.Technology TypeDigital HealthTechnology SubtypeClinical Decision SupportTherapeutic AreasHematologyTherapeutic IndicationsThrombosisTagsArtificial intelligence (AI)AlgorithmCritical CareLead InventorCatalin TomaDepartmentMed-MedicineAll Tech InnovatorsMurat AkcakayaSalah Shafiq Al-ZaitiTanmay Anil GokhaleTechnology Readiness Level4. Prototype testing and refinementDate Submitted2025-05-14CollectionsHealthcare AI
spatiAlytica: AI-Driven Spatial Transcriptomic Discovery with Multi-Agent Large Language Models06900AI tool lets non-coders query, analyze, and visualize spatial transcriptomics in real-time using natural language.Technology TypeLife Science Research ToolTechnology SubtypeBioinformaticsLead InventorYufei HuangDepartmentMed-MedicineAll Tech InnovatorsArun DasYufei HuangDate Submitted2024-09-25CollectionsHealthcare AI
Training: Impact of Stigma of Substance Use, Recovery06857A physician training program reduces substance-use stigma through patient-centered language, improving care access, engagement, and recovery outcomes.Technology TypeDigital HealthTechnology SubtypeClinical Decision SupportTagsEducation TechnologyLead InventorHeather SantaDepartmentMed-MedicineAll Tech InnovatorsHeather Marie SantaDate Submitted2024-08-28
Handheld Oscillating Device of Vascular Interventions06595A handheld ERM-driven torquing device eases guidewire navigation in vascular interventions, lowering trauma risk and costs.Technology TypeMedical DeviceTechnology SubtypeSurgical Medical DeviceTherapeutic AreasCardiovascularTherapeutic IndicationsAtherosclerotic diseaseLead InventorCatalin TomaDepartmentMed-MedicineAll Tech InnovatorsJared D. RomeoCatalin TomaDate Submitted2023-12-13CollectionsCardiometabolic
Measuring Environmental Determinants of Health by Geographical Information (MEDGI)06351MEDGI streamlines environmental data retrieval and geolocation-based air pollution modeling for multiple years, easing analytics.Technology TypeDigital HealthTechnology SubtypeHealthcare DataTagsPublic HealthSoftwareLead InventorSeyed NouraieDepartmentMed-MedicineAll Tech InnovatorsMatthew James BroermanSeyed Mehdi NouraieTechnology Readiness Level4. Prototype testing and refinementDate Submitted2023-03-10
Microbiome Analysis to Predict Immunotherapy Response05640Gut microbiome signatures predict anti-PD-1 therapy response, PFS, and irAEs, guiding personalized cancer immunotherapy.Technology TypeDiagnostic/AssayTechnology SubtypeBiomarkerTherapeutic AreasOncologyTherapeutic IndicationsLung cancer - otherTagsClinical Decision SupportLife ScienceLead InventorDiwakar DavarDepartmentMed-MedicineAll Tech InnovatorsDiwakar DavarAmiran DzutsevJohn McCullochDate Submitted2021-03-16
NAMPT Inhibitors Exhibit Excellent Potency and ADME Properties05522Novel Nampt inhibitors deliver strong potency and favorable ADME, enabling chemotherapy and immune support benefits.Technology TypeTherapeutic ModalityTechnology SubtypeSmall MoleculeTherapeutic AreasImmunologyOncologyTagsAutoimmuneImmuno-oncologyLead InventorBeibei ChenDepartmentMed-MedicineAll Tech InnovatorsBeibei ChenToren FinkelYuan LiuTechnology Readiness Level3. Initial proof of concept, in-vivoDate Submitted2020-10-06
Secretome Mouse Model05233Secretome mouse reveals tissue-specific protein secretion in vivo, enabling biomarker discovery and insights into exercise-induced proteome changes.Technology TypeLife Science Research ToolTechnology SubtypeAnimal ModelTherapeutic AreasMusculoskeletalLead InventorToren FinkelDepartmentMed-MedicineAll Tech InnovatorsToren FinkelJie LiuDate Submitted2020-01-25
Enhanced Antitumor Efficacy of Ultrasound-mediated Doxorubicin Delivery by Microbubble-liposome Complex05168Ultrasound-triggered microbubble-liposome delivery of doxorubicin enhances tumor kill, reduces cardiotoxicity, boosting soft-tissue sarcoma therapy.Technology TypeTherapeutic ModalityTechnology SubtypeDrug Delivery / FormulationTherapeutic AreasOncologyTherapeutic IndicationsSolid tumorLead InventorFlordeliza VillanuevaDepartmentMed-MedicineAll Tech InnovatorsXucai ChenMingyu HeFlordeliza S. Villanueva M.D.Technology Readiness Level3. Initial proof of concept, in-vivoDate Submitted2019-11-14
Targeting Cardiomyocyte Endoreplication to Prevent Hypertrophic Cardiomyopathy07132Inhibits PCNA-POLD1 interactions via p21 to curb cardiomyocyte endoreplication, preventing hypertrophic cardiomyopathy progression.Technology TypeTherapeutic ModalityTechnology SubtypeGene Therapy - RNATherapeutic AreasCardiovascularTherapeutic IndicationsHypertrophic cardiomyopathyTagsGeneticsRegenerative medicinePlatform TechnologyLead InventorJason BeckerDepartmentMed-MedicineAll Tech InnovatorsJason Robert BeckerSoumojit PalTechnology Readiness Level4. Pre-clinical developmentDate Submitted2025-03-30CollectionsCell & Gene TherapyRegenerative MedicineCardiometabolic
Opioid Use Disorder Medication Training Program for Health Professionals06869Comprehensive FDA‑MOUD training for primary care pros, boosting OUD treatment quality, engagement, and outcomes with case worker roles.Technology TypeOtherTherapeutic AreasMental and Behavioral HealthTherapeutic IndicationsOpiod use disorderLead InventorHeather SantaDepartmentMed-MedicineAll Tech InnovatorsHeather Marie SantaDate Submitted2024-09-06
Device for Collecting Exhaled Aerosols During Mechanical Ventilation06109Non-invasive device collects exhaled aerosols from ventilated patients for frequent VAP monitoring and rapid pathogen detection.Technology TypeMedical DeviceTechnology SubtypeMonitoring Medical DeviceTherapeutic AreasInfectious DiseaseRespiratoryTherapeutic IndicationsOtherTagsMinimally invasiveLead InventorTimothy CorcoranDepartmentMed-MedicineAll Tech InnovatorsTimothy E. CorcoranSteven George Kefalos IIRutuja Amar KulkarniTechnology Readiness Level4. Prototype testing and refinementDate Submitted2022-07-25
Accelerated Wound Healing Sustained Release Nanoparticles07150Sustained-release TGF-β3 nanoparticles enhance soft-tissue wound strength, reduce scarring, enabling single-site surgical therapy.TagsImplantable Medical DeviceMaterial ScienceLead InventorThiagarajan MeyyappanDepartmentMed-MedicineAll Tech InnovatorsSteven R. LittleThiagarajan MeyyappanDate Submitted2025-04-15CollectionsRegenerative Medicine
Better Than OK: Enhanced Proximal Tubule Cell Models for Drug Development and Nephrotoxicity Testing06911Enhanced opossum kidney proximal tubule model with CRISPR knockouts for megalin/Dab2; predictive nephrotoxicity and drug-screening tool.Technology TypeLife Science Research ToolTechnology SubtypeCell LineTherapeutic AreasNephrologyTagsDrug DevelopmentDrug Discovery - TargetLead InventorOra WeiszDepartmentMed-MedicineAll Tech InnovatorsKimberly R. LongYoussef RbaibiOra Anna WeiszTechnology Readiness Level3. Prototype developmentDate Submitted2024-10-02
Whole Genome Sequencing Analytic Pipeline for Healthcare Associated Transmission05332Whole-genome sequencing plus ML and EHRs enables real-time hospital outbreak detection and targeted infection control.Technology TypeDigital HealthTechnology SubtypeHealthcare DeliveryTherapeutic AreasInfectious DiseaseLead InventorLee HarrisonDepartmentMed-MedicineAll Tech InnovatorsArtur Wladyslaw DubrawskiLee H. HarrisonDate Submitted2020-05-01CollectionsHealthcare AI
Novel Treatment for Neuroblastoma and Ewing Sarcoma07186Fully human GFRA2-targeting antibodies offer precision immunotherapy for pediatric neuroblastoma and Ewing sarcoma, adaptable to multiple modalities.Technology TypeTherapeutic ModalityTechnology SubtypeAntibody - mAbTherapeutic AreasOncologyTherapeutic IndicationsGlioblastomaTagsLife ScienceLead InventorWei LiDepartmentMed-MedicineAll Tech InnovatorsSharon DiskinAmber HamiltonWei LiDate Submitted2025-05-14
Novel Patient-Derived Assembloid Model Accelerates Immunotherapy Development for Difficult-to-Treat Cancers06922Patient-derived assembloid with tumor-immune co-cultures accelerates immunotherapy/vaccine development for hard-to-treat head and neck cancers.Technology TypeLife Science Research ToolTechnology SubtypeCell LineTherapeutic AreasImmunologyOncologyTherapeutic IndicationsSolid tumorTagsImmuno-oncologyTissue engineeringPlatform TechnologyLead InventorRiyue BaoDepartmentMed-MedicineAll Tech InnovatorsRiyue BaoJason J. LukeTechnology Readiness Level3. Prototype developmentDate Submitted2024-10-16
Novel Llama Nanobody to Treat HIV-106827Humanized llama nanobody 4E2 neutralizes diverse HIV-1 variants, mimicking CD4 with low immunogenicity, promising therapy.Technology TypeTherapeutic ModalityTechnology SubtypeAntibody - mAbTherapeutic AreasImmunologyInfectious DiseaseTherapeutic IndicationsHIVTagsDrug Discovery - TargetLife ScienceLead InventorWei LiDepartmentMed-MedicineAll Tech InnovatorsZhiwei FengMargaret Grace HinesWei LiDate Submitted2024-07-26CollectionsWomen's & Reproductive HealthHealthcare AI
Novel Treatment for Retinitis Pigmentosa06383Pyrvinium targets NS LLPS to restore proteostasis, preserve retinal structure, and may treat retinitis pigmentosa and proteinopathies.Technology TypeTherapeutic ModalityTechnology SubtypeSmall MoleculeTherapeutic AreasNeuroscienceOphthalmologyTherapeutic IndicationsParkinson's DiseaseAlzheimer's DiseaseRetinitis pigmentosa (RP)TagsLife ScienceLead InventorBokai ZhuDepartmentMed-MedicineAll Tech InnovatorsYuanyuan ChenWilliam A. DionBokai ZhuDate Submitted2023-04-23
Algorithm to Improve High-Throughput Microscopy06142Adaptive AID drift-correction enables real-time, marker-free, high-throughput SMLM with sub-nanometer precision.Technology TypeLife Science Research ToolTechnology SubtypeOther Life Science Research ToolTagsMicroscopyLead InventorHongqiang MaDepartmentMed-MedicineAll Tech InnovatorsYang LiuHongqiang MaDate Submitted2022-08-24
miniSTORM: Compact and Accessible Nanoscopy05666Compact, automated all-in-one nanoscopy enabling bench-top super-resolution imaging at lower cost and broader accessibility.Technology TypeLife Science Research ToolTechnology SubtypeOther Life Science Research ToolTagsLife ScienceLead InventorHongqiang MaDepartmentMed-MedicineAll Tech InnovatorsYang LiuHongqiang MaDate Submitted2021-04-12
Near Real-Time Composite Pulmonary Vascular Impedance Software05304Near real-time PVZ spectrum tool with FFT from pressure/flow data, giving comprehensive, bedside right-heart afterload insights.Technology TypeDigital HealthTechnology SubtypeClinical Decision SupportTherapeutic AreasCardiovascularTherapeutic IndicationsHeart failureLead InventorTimothy BachmanDepartmentMed-MedicineAll Tech InnovatorsTimothy Nicholas BachmanMarc Alan SimonDate Submitted2020-04-13CollectionsCardiometabolic
Madin Darby Canine Kidney (MDCK) Cells Expressing the Epithelial Na+ Channel (ENaC)01434MDCK cells engineered with mouse ENaC subunits enable study of channel biosynthesis, trafficking, and inhibitor screening.Technology TypeLife Science Research ToolTechnology SubtypeCell LineTherapeutic AreasNephrologyLead InventorThomas KleymanDepartmentMed-MedicineAll Tech InnovatorsJames B. BrunsRebecca P. Hughey Ph.D.Thomas Ralph KleymanDate Submitted2007-02-03
Next-Generation Long-Lasting Soluble CD4-D1 Domains as HIV Entry Inhibitors06603Engineered soluble CD4-D1 variant offers long-lasting HIV entry inhibition with enhanced stability, MHC II avoidance, and broad neutralization.Technology TypeTherapeutic ModalityTechnology SubtypeAntibody - BispecificTherapeutic AreasInfectious DiseaseTherapeutic IndicationsHIVLead InventorWei LiDepartmentMed-MedicineAll Tech InnovatorsXiaojie ChuJana Lynn JacobsWei LiTechnology Readiness Level3. Initial proof of concept, in-vivoDate Submitted2024-01-08CollectionsWomen's & Reproductive Health
Hyper-throughput Biomarker Detection06165Ultra-high-throughput single-molecule exosome biomarker detection platform enabling ultra-sensitive, multiplexed disease diagnostics and monitoring.Technology TypeLife Science Research ToolTechnology SubtypeOther Life Science Research ToolTagsMicroscopyLead InventorHongqiang MaDepartmentMed-MedicineAll Tech InnovatorsYang LiuHongqiang MaDate Submitted2022-09-16
Fully Human Fab and VH Antibody Binding to SIRPa06871Fully human antibodies block SIRPα–CD47, restore macrophage phagocytosis, boosting cancer immunotherapy potential.Technology TypeTherapeutic ModalityTechnology SubtypeAntibody - FabTherapeutic AreasOncologyLead InventorSeungmin ShinDepartmentMed-MedicineAll Tech InnovatorsDimiter Stanchev DimitrovWei LiJohn W. MellorsTechnology Readiness Level2. Initial proof of concept, in-vitroDate Submitted2024-09-09
Fully Human Fab and VH Antibody Binding to PLA2G706870Fully human antibodies block PLA2G7 to reduce inflammation, with potential anti-aging and cancer therapies.Technology TypeTherapeutic ModalityTechnology SubtypeAntibody - BispecificTherapeutic AreasOncologyCardiovascularTherapeutic IndicationsStrokeAtherosclerotic diseaseTagsAgingLead InventorSeungmin ShinDepartmentMed-MedicineAll Tech InnovatorsDimiter Stanchev DimitrovWei LiJohn W. MellorsTechnology Readiness Level2. Initial proof of concept, in-vitroDate Submitted2024-09-09CollectionsCardiometabolic
Modified splitFAST Tool to Detect TERT and STAT5 Interaction06785Real-time, TERT-STAT5 interaction visualization via modified splitFAST; cell-level, spatial-temporal protein interaction insights for research.Technology TypeLife Science Research ToolTechnology SubtypeNucleic AcidLead InventorCynthia St HilaireDepartmentMed-MedicineAll Tech InnovatorsCynthia L. St HilaireDate Submitted2024-06-26
Innovative Gene Therapy for Heart Disease: p21 Overexpression in Cardiomyocytes06708AAV9-delivered p21 overexpression in cardiomyocytes reduces hypertrophic remodeling and improves diastolic function in mouse models.Technology TypeTherapeutic ModalityTechnology SubtypeGene Therapy - AAVTherapeutic AreasCardiovascularTherapeutic IndicationsHypertrophic cardiomyopathyLead InventorJason BeckerDepartmentMed-MedicineAll Tech InnovatorsJason Robert BeckerSoumojit PalTechnology Readiness Level3. Initial proof of concept, in-vivoDate Submitted2024-04-03CollectionsCell & Gene TherapyCardiometabolic
Virtual Health Coach Bridges Rural Cardiovascular Care Gaps06539A rural-focused virtual health coach delivers empathic, personalized cardiovascular coaching with home monitoring integration for chronic disease.Technology TypeDigital HealthTechnology SubtypeOther Digital HealthTherapeutic AreasCardiovascularEndocrinology and Metabolic DiseasesTherapeutic IndicationsPulmonary arterial hypertension (PAH)DiabetesLead InventorJared MagnaniDepartmentMed-MedicineAll Tech InnovatorsBrian KaleidaJared William MagnaniDate Submitted2023-10-10CollectionsCardiometabolic
A Novel Treatment Target for Pulmonary Hypertension05987A non-coding SNV in KMT2E links HIF-driven epigenetic changes to pulmonary hypertension, suggesting targeted diagnostics and one-off therapies.Technology TypeTherapeutic ModalityTechnology SubtypeDrug Discovery - TargetTherapeutic AreasCardiovascularTherapeutic IndicationsPulmonary arterial hypertension (PAH)Lead InventorStephen ChanDepartmentMed-MedicineAll Tech InnovatorsStephen Yu-Wah Chan MD, PhDTechnology Readiness Level3. Initial proof of concept, in-vivoDate Submitted2022-03-17CollectionsCardiometabolic
Microfluidic System Rapidly Isolates Extracellular Vesicles from Biological Fluids05658Automated microfluidic device rapidly, fractionally isolating all extracellular vesicle sizes and large cells from fluids in seconds.Technology TypeLife Science Research ToolTechnology SubtypeOther Life Science Research ToolTherapeutic AreasOtherTagsPlatform TechnologyLead InventorKambez Hajipouran BenamDepartmentMed-MedicineAll Tech InnovatorsKambez Hajipouran BenamAlexander Joseph KaiserDate Submitted2021-04-04
Novel Activators of AMP-activated Protein Kinase03887New nanomolar small molecules block AMPK ubiquitination, stabilizing and activating AMPK to treat metabolic, inflammatory, and cancer disorders.Technology TypeTherapeutic ModalityTechnology SubtypeSmall MoleculeTherapeutic AreasCardiovascularEndocrinology and Metabolic DiseasesTagsAgingLead InventorBeibei ChenDepartmentMed-MedicineAll Tech InnovatorsBeibei ChenYuan LiuRama K. MallampalliTechnology Readiness Level3. Initial proof of concept, in-vivoDate Submitted2016-04-05CollectionsCardiometabolic
Microbubble-Based Sonosensitizer Delivery Systems for Ultrasound-Triggered Reactive Oxygen Species Generation and Cancer Therapy04132Ultrasound-triggered lipid microbubbles deliver hydrophobic sonosensitizers for targeted ROS-based cancer therapy with theranostic imaging.Technology TypeTherapeutic ModalityTechnology SubtypeDrug Delivery / FormulationTherapeutic AreasOncologyTherapeutic IndicationsSolid tumorLead InventorXucai ChenDepartmentMed-MedicineAll Tech InnovatorsXucai ChenBin QinFlordeliza S. Villanueva M.D.Date Submitted2017-01-19
Novel Senotherapeutic Agents for Cancer Therapy06267Senotherapeutic sGC activator cinaciguat induces apoptosis in senescent prostate cancer cells, reducing recurrence and BPH progression.Technology TypeTherapeutic ModalityTechnology SubtypeSmall MoleculeTherapeutic AreasUrologyOncologyTherapeutic IndicationsProstate cancer / adenocarcinomaTagsAgingLead InventorAnthony KanaiDepartmentMed-MedicineAll Tech InnovatorsYouko IkedaAnthony J. KanaiIrina Valerjevna ZabbarovaTechnology Readiness Level3. Initial proof of concept, in-vivoDate Submitted2023-01-12
Depth-Resolved Low-Coherence Phase Microscopy for Quantitative 3D Imaging of Stained and Unstained Tissues03378Depth-resolved, label-free 3D tissue imaging with tunable white-light phase microscopy; integrates staining, autofocus, and automated nuclear segmentation.Technology TypeLife Science Research ToolTechnology SubtypeOther Life Science Research ToolTherapeutic AreasOtherLead InventorYang LiuDepartmentMed-MedicineAll Tech InnovatorsYang LiuHoa Vinh PhamShikhar UttamDate Submitted2014-08-12
Immunotherapy for Neuroblastoma and Ewing Sarcoma07259GFRA2-targeted humanized antibodies enable precision immunotherapy (CAR T, ADCs) for neuroblastoma and Ewing sarcoma. Technology TypeTherapeutic ModalityTechnology SubtypeDrug Discovery - TargetTherapeutic AreasOncologyTherapeutic IndicationsNeuroblastomaGlioblastomaTagsLife ScienceLead InventorWei LiDepartmentMed-MedicineAll Tech InnovatorsSharon DiskinAmber HamiltonMichelle KeyelTechnology Readiness Level3. Initial proof of concept, in-vivoDate Submitted2025-07-29
Extended Reality System for Controlling Operating Room Tools06638XR-based holographic control of non-sterile OR tools enhances sterility, security, and efficiency via bidirectional tool interfacing.Technology TypeMedical DeviceTechnology SubtypeSurgical Medical DeviceTagsSurgeryLead InventorNicolas KassDepartmentMed-MedicineAll Tech InnovatorsEdward Gregory AndrewsJacob BiehlGriffin James HurtDate Submitted2024-02-10
Novel Strategy to Prevent Cardiomyopathy06477Targeting MDM2 to prevent left ventricular hypertrophy and microvascular dysfunction, potentially halting hypertrophic cardiomyopathy progression.Technology TypeTherapeutic ModalityTechnology SubtypeDrug Discovery - TargetTherapeutic AreasCardiovascularLead InventorJason BeckerDepartmentMed-MedicineAll Tech InnovatorsJason Robert BeckerTechnology Readiness Level3. Initial proof of concept, in-vivoDate Submitted2023-08-08CollectionsCardiometabolic
Web-based Application for Integrating Cancer Genetic Vulnerabilities and Drug Sensitivities06421Integrated web tool linking cancer gene vulnerabilities with drug sensitivities via CRISPR, expression, and pharmacology data.Technology TypeLife Science Research ToolTechnology SubtypeBioinformaticsTherapeutic AreasOncologyTagsPersonalized MedicineDrug DevelopmentDrug Discovery - TargetLead InventorYu-Chiao ChiuDepartmentMed-MedicineAll Tech InnovatorsYidong ChenYu-Chiao ChiuTapsya NayakDate Submitted2023-05-31
Enzyme Inhibitor Promotes Anticancer Immune Response05716Enzyme ALDH1A inhibitor boosts antitumor immunity, enhances vaccine efficacy, and improves tumor control in hard-to-treat cancers.Technology TypeTherapeutic ModalityTechnology SubtypeSmall MoleculeTherapeutic AreasInfectious DiseaseOncologyTagsImmuno-oncologyLead InventorRonald BuckanovichDepartmentMed-MedicineAll Tech InnovatorsRonald J. BuckanovichAnda Mioara VladTechnology Readiness Level3. Initial proof of concept, in-vivoDate Submitted2021-06-08CollectionsWomen's & Reproductive Health
Targeted Treatment of Inflammatory Bowel Disease05417Orally delivered, targeted PLGA microparticles deliver IL-2, TGF-β, and rapamycin to inflamed gut tissue, reducing IBD activity.Technology TypeTherapeutic ModalityTechnology SubtypeDrug Delivery / FormulationTherapeutic AreasGastroenterologyImmunologyTherapeutic IndicationsChrohn's DiseaseLead InventorRoger SandsDepartmentMed-MedicineAll Tech InnovatorsSteven R. LittleRoger Warren SandsTechnology Readiness Level3. Initial proof of concept, in-vivoDate Submitted2020-06-11
