Technology Type

Diagnostic/Assay

Novel Diagnostic Biomarker for Alzheimer's Disease

06770

Ultrasensitive CSF assay detects early pre-tangle soluble tau assemblies, enabling earlier Alzheimer’s diagnosis and targeted therapies.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Neuroscience
Therapeutic Indications: Alzheimer's Disease
Lead Inventor: Thomas Karikari
Department: Med-Psychiatry
All Tech Innovators: Eric E. Abrahamson
Milos Dragan Ikonomovic MD
Thomas K. Karikari
Date Submitted: 2024-06-10

Highly Accurate Serological Biomarker for Early Detection of Nasopharyngeal Carcinoma

05923

A serological panel detects EBV EBNA1 IgA with 100% sensitivity/specificity, enabling pre-diagnostic NPC risk screening.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Therapeutic Indications: Nasopharyngeal carcinoma (NPC)
Solid tumor
Lead Inventor: Kathy Ho Yen Shair
Department: Med-Microbiology and Molecular Genetics
All Tech Innovators: Kathy Ho Yen Shair
Jian-Min Yuan
Date Submitted: 2021-12-20

Novel Biomarker Tools for Tauopathies

06769

New tau-targeting antibodies enable blood tests for early tauopathies, offering noninvasive diagnosis and treatment insight.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Neuroscience
Therapeutic Indications: Alzheimer's Disease
Lead Inventor: Thomas Karikari
Department: Med-Psychiatry
All Tech Innovators: Thomas K. Karikari
Xuemei Zeng
Date Submitted: 2024-06-06

Post-Cardiac Arrest Classification Mobile and Web App

06035

Real-time PCAC scoring app for bedside cardiac arrest patients, improving outcomes, workflow, and cross-center comparisons.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Cardiovascular
Therapeutic Indications: Other
Lead Inventor: Ankur Doshi
Department: Med-Emergency Medicine
All Tech Innovators: Gabriel Lucas Diamond
Ankur Ashok Doshi
Date Submitted: 2022-05-19
Collections: Cardiometabolic

Anticholinergic Medication Management System: Patient-Centered Tools for Safer Deprescribing and Side Effect Monitoring

05230

Patient-centered PASS v2 and Shared Decision Making infographic enable safer deprescribing, symptom monitoring, and collaborative anticholinergic care.

Technology Type: Diagnostic/Assay
Lead Inventor: Kadiamada Chengappa
Department: Med-Psychiatry
All Tech Innovators: Jaspreet Singh Brar
Kadiamada N. Chengappa
Jessica Michelle Gannon
Date Submitted: 2020-01-23

Streamlined Resource–Efficient Assay for Amyloid-β

06792

A streamlined IP-MS assay uses a common buffer to quantify plasma amyloid-β biomarkers, enabling affordable, noninvasive AD monitoring.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Neuroscience
Therapeutic Indications: Alzheimer's Disease
Tags: In Vitro Diagnostic
Life Science
Lead Inventor: Thomas Karikari
Department: Med-Psychiatry
All Tech Innovators: Yijun Chen
Thomas K. Karikari
Nathan A. Yates
Date Submitted: 2024-07-05

B Cell-Based Biomarker for Detecting Acute Renal Transplant Rejection

06574

A blood test using B cell markers and machine learning detects acute renal transplant rejection noninvasively with high accuracy.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Nephrology
Immunology
Therapeutic Indications: Other
Lead Inventor: David Rothstein
Department: Med-Surgery
All Tech Innovators: Aravind Cherukuri
David Mark Rothstein
Date Submitted: 2023-11-27

Integrated AI and Sensing System for Pulmonary Disease Evaluation

06395

AI-enabled smartphone system (PTEase) remotely analyzes airway measurements for lung function and disease classification.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Respiratory
Lead Inventor: Wei Gao
Department: Electrical and Computer Engineering
All Tech Innovators: Wei Chen
Erick Forno
Wei Gao
Date Submitted: 2023-05-03
Collections: Healthcare AI

Novel Approach to Rapid Hearing Loss Assessment

06185

Non-invasive EEG-based test blends tailored sounds and algorithms to objectively diagnose perception-related hearing loss.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Otolaryngology
Therapeutic Indications: Hearing Loss
Lead Inventor: Aravindakshan Parthasarathy
Department: SHRS-Commu Science & Disorders
All Tech Innovators: Edward L. Bartlett
Satyabrata Parida
Aravindakshan Parthasarathy
Date Submitted: 2022-10-16

Microbiome Analysis to Predict Immunotherapy Response

05640

Gut microbiome signatures predict anti-PD-1 therapy response, PFS, and irAEs, guiding personalized cancer immunotherapy.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Therapeutic Indications: Lung cancer - other
Tags: Clinical Decision Support
Life Science
Lead Inventor: Diwakar Davar
Department: Med-Medicine
All Tech Innovators: Diwakar Davar
Amiran Dzutsev
John McCulloch
Date Submitted: 2021-03-16

Biomarkers for Diagnosis of Ear and Sinus Infections

07147

A nasal biomarker (IL-1a) plus symptom scores enables precise pediatric bacterial sinusitis diagnosis and antibiotic stewardship.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Otolaryngology
Tags: Biomarker
Clinical Decision Support
Life Science
Lead Inventor: Nader Shaikh
Department: Med-Pediatrics
All Tech Innovators: Nader Shaikh
Date Submitted: 2025-04-11

Rapid Electrochemical Screen for Illicit Drugs

06703

Automated 96-sensor electrolyte-gated FET platform rapidly screens illicit drugs with high-throughput, streamlined lab workflows.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Mental and Behavioral Health
Lead Inventor: Alexander Star
Department: Chemistry
All Tech Innovators: Zhengru Liu
Alexander Star
Date Submitted: 2024-03-27

A Novel Therapeutic Biomarker for Metabolic Liver Disease

06324

Identifies PNPLA3 rs738409 variant driving MAFLD via ferroptosis; enables targeted therapies, screening, and safer liver transplantation.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Hepatology
Therapeutic Indications: End-Stage liver disease (ESLD)
Cirrhosis
Tags: Drug Discovery - Target
Life Science
Liver Disease
Lead Inventor: Alejandro Soto Gutierrez
Department: Med-Pathology
All Tech Innovators: Abhinav Achreja
Olamide Animasahun
Rodrigo Machado Florentino
Date Submitted: 2023-03-01
Collections: Cardiometabolic

RNA- and DNA-Based Assays for Predicting Paclitaxel Resistance in Triple Negative Breast Cancer

05224

RNA- and DNA-based assays identify a TNBC-specific fusion linked to paclitaxel resistance, enabling therapy pivots.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Therapeutic Indications: Ductal carcinoma (Breast cancer)
Lead Inventor: Xiaosong Wang
Department: Med-Pathology
All Tech Innovators: Xiaosong Wang
Date Submitted: 2020-01-17
Collections: Women's & Reproductive Health

Resolving Diagnostic Discrepancies in Multiple Myeloma Patients

04607

Magnetic bead-based depletion removes therapeutic monoclonal antibodies, reducing false positives in MM diagnostics and treatment monitoring.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Oncology
Hematology
Tags: Coating
Immuno-oncology
Lead Inventor: Sarah Wheeler
Department: Med-Pathology
All Tech Innovators: Li Liu
Michael R. Shurin
Sarah Elizabeth Wheeler
Date Submitted: 2018-04-26

Novel Assessment for Cutaneous T Cell Lymphoma

02958

Proposes a genetic CTCL diagnostic signature (TOX, RUNX3, GATA3) to diagnose, gauge severity, and tailor treatment.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Therapeutic Indications: Melanoma
Lead Inventor: Larisa Geskin
Department: Med-Dermatology
All Tech Innovators: Brittany Lynn O'Neill Dulmage
Louis D. Falo Jr
Larisa J. Geskin
Date Submitted: 2013-01-08

Non-Invasive Detection of HPV+ and Throat Cancers

06558

Non-invasive device irrigates lesions to harvest cfDNA for HPV+ throat cancer risk via NGS, reducing biopsies.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Oncology
Lead Inventor: Jose Zevallos
Department: Med-Otolaryngology
All Tech Innovators: Jose P. Zevallos
Date Submitted: 2023-11-03
Collections: Women's & Reproductive Health

Novel Biosensor to Detect Fentanyl Exposure

06287

Ultra-sensitive carbon nanotube FET biosensor detects norfentanyl in minutes (fg/mL), enabling rapid point-of-care fentanyl exposure screening.

Technology Type: Diagnostic/Assay
Therapeutic Areas: Other
Lead Inventor: Alexander Star
Department: Chemistry
All Tech Innovators: Wenting Shao
Alexander Star
Date Submitted: 2023-02-09

SWeeTT: Solitary Wave-based easily-employable Trans-palpebral Tonometer

04573

SWeeTT enables easy, at-home, trans-palpebral intraocular pressure monitoring with daily data and clinician connectivity.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Ophthalmology
Lead Inventor: Piervincenzo Rizzo
Department: Civil & Environmental Engineering
All Tech Innovators: Amir Nasrollahi
Piervincenzo Rizzo
Date Submitted: 2018-03-31

MATS Proteomics Test

05511

Hybrid mass-spectrometry + ML platform enabling absolute, high-throughput proteome quantitation for biomarker discovery and clinical diagnostics.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Lead Inventor: Kunhong Xiao
Department: Med-Pharmacology and Chemical Biology
All Tech Innovators: Fei Fang
Kunhong Xiao
Date Submitted: 2020-09-24

Epstein-Barr Circular RNA as a Novel Biomarker of EBV-Related Cancers

04470

Stable EBV circBART circular RNAs enable rapid, low-cost, reliable cancer detection and early diagnosis in diverse tumors.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Oncology
Infectious Disease
Therapeutic Indications: Lymphoma
Herpes
Lead Inventor: Patrick Moore
Department: Med-Pathology
All Tech Innovators: Yuan Chang
Patrick S. Moore
Tuna Toptan
Date Submitted: 2018-01-02

Eomesodermin as a Biomarker for Allograft Rejection

03456

Eomesodermin as a noninvasive biomarker predicts transplant rejection risk by monitoring memory T cell activity to guide therapy.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Surgery
Immunology
Therapeutic Indications: Other
Lead Inventor: Mohamed Ezzelarab
Department: Med-Surgery
All Tech Innovators: Mohamed Borhami Ezzelarab
Angus W. Thomson
Date Submitted: 2014-11-25

Novel Biomarker for Personalizing Cancer

06959

10-gene interferon/exhaustion signature predicts which HNSCC patients will benefit from specific PD-1+LAG-3 immunotherapy.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Tags: Biomarker
Personalized Medicine
Life Science
Lead Inventor: Robert Ferris
Department: Med-Otolaryngology
All Tech Innovators: Robert Louis Ferris
Housaiyin Li
Lazar Nikola Vujanovic
Date Submitted: 2024-11-06

Fusion Gene-Based Machine Learning Tool Enhances Prediction of Prostate Cancer Clinical Outcomes

06089

Fusion-gene based machine learning boosts prostate cancer recurrence predictions using 14 gene signatures across multiple cohorts.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Urology
Oncology
Therapeutic Indications: Prostate cancer / adenocarcinoma
Tags: Genetics
Lead Inventor: Jianhua Luo
Department: Med-Pathology
All Tech Innovators: Shuchang Liu
Jianhua Luo
George Michalopoulos
Date Submitted: 2022-07-01

Early Warning System for Preventing Necrotizing Enterocolitis (NEC) in Preterm Infants

05327

AI-driven NEC risk predictor for preterm infants using stool microbiome data, clinical features, enabling early intervention. 132 characters

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Gastroenterology
Therapeutic Indications: Other
Tags: Machine learning
Lead Inventor: Thomas Hooven
Department: Med-Pediatrics
All Tech Innovators: Thomas Hooven
Yun Chao Lin
Ansaf Salleb-Aouissi
Date Submitted: 2020-04-29
Collections: Healthcare AI

Methods for Predicting and Monitoring Responsiveness to Multiple Myeloma Therapy

03913

A biomarker-based method using Ser288-phosphorylated hXBP1s to predict and monitor myeloma therapy response, guiding personalized treatment.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Therapeutic Indications: Multiple Myeloma
Tags: Drug Repurposing
Lead Inventor: Hongjiao Ouyang
Department: Dent Med-Oral Biology
All Tech Innovators: Hongjiao Ouyang
Date Submitted: 2016-04-19

A Novel Neoplastic Fusion Transcript Predicts Sensitivity to the MEK Inhibitor Trametinib in More Aggressive and Metastatic Breast Cancers

05317

Fusion RAD51AP1-DYRK4 predicts trametinib sensitivity in aggressive/metastatic breast cancers, enabling targeted MEK inhibitor therapy.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Therapeutic Indications: Ductal carcinoma (Breast cancer)
Tags: Precision medicine
Personalized Medicine
Women's Health
Lead Inventor: Xiaosong Wang
Department: Med-Pathology
All Tech Innovators: Chia Chia Liu
Xiaosong Wang
Date Submitted: 2020-04-22
Collections: Women's & Reproductive Health

Novel Biomarker to Detect CMV T Cell Immunity

04855

KLRG1-based assay predicts CMV T cell immunity in transplant patients, enabling targeted antiviral therapy.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Immunology
Infectious Disease
Lead Inventor: John McDyer
Department: Med-Medicine
All Tech Innovators: Akihiko Hoji
John Francis McDyer
Iulia-Dana Popescu
Date Submitted: 2019-01-09

AOM-SOS Version 5.0: Enhanced Psychometric Scale for Acute Otitis Media

04070

Enhanced AOM-SOS 5.0: six-point pediatric otitis media symptom scale with improved reliability for clinical use and research.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Otolaryngology
Therapeutic Indications: Other
Lead Inventor: Nader Shaikh
Department: Med-Pediatrics
All Tech Innovators: Alejandro Hoberman
Jack L. Paradise
Nader Shaikh
Date Submitted: 2016-11-07

Novel Transcriptional Signature for Chlamydial PID

03188

Novel gene-expression biomarkers enable low-cost, minimally invasive detection of asymptomatic chlamydial PID and endometritis.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Reproductive Health
Infectious Disease
Tags: Autoimmune
Lead Inventor: Catherine O'Connell
Department: Pediatrics
All Tech Innovators: Lee Antoinette Darville
Catherine Mary O'Connell
Xiaojing Zheng
Date Submitted: 2013-12-06
Collections: Women's & Reproductive Health

Personalized Pain Management: Predicting Chronic Pain Post-Mastectomy

02280

Personalized post-mastectomy pain risk profiling using genetic and psychosocial data to tailor perioperative care.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Neuroscience
Oncology
Therapeutic Indications: Pain
Ductal carcinoma (Breast cancer)
Tags: Genetics
Personalized Medicine
Clinical Decision Support
Lead Inventor: Inna Belfer
Department: GSPH-Human Genetics
All Tech Innovators: Inna Belfer
Feng Dai
Technology Readiness Level: 4. Proof of concept
Date Submitted: 2010-08-22
Collections: Women's & Reproductive Health

Novel Therapy to Prevent Liver Disease

05722

Targeting ferroptosis to prevent PNPLA3 rs738409:G-linked liver cirrhosis, offering non-invasive therapy and reduced transplant need.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Hepatology
Therapeutic Indications: Non-alcoholic steatohepatitis (NASH)
Cirrhosis
Tags: Genetics
Lead Inventor: Alejandro Soto Gutierrez
Department: Med-Pathology
All Tech Innovators: Abhinav Achreja
Olamide Animasahun
Rodrigo Machado Florentino
Date Submitted: 2021-06-10
Collections: Cardiometabolic

E-cadherin as a Biomarker of Response to Anti-IGF1R Inhibitors

04468

E-cadherin loss predicts and enhances response to anti-IGF1R therapy, enabling personalized cancer treatment strategies.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Therapeutic Indications: Ductal carcinoma (Breast cancer)
Lead Inventor: Adrian Lee
Department: Med-Pharmacology and Chemical Biology
All Tech Innovators: Adrian Vincent Lee
Alison Mary Nagle
Steffi Oesterreich
Date Submitted: 2017-12-24
Collections: Women's & Reproductive Health

Urinary Biomarkers for Predicting Long-Term Dialysis

01776

Urinary hyaluronic acid as a non-invasive biomarker predicts long-term dialysis risk after AKI, enabling early CKD prevention.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Intensive Care
Nephrology
Lead Inventor: Kai Singbartl
Department: Department of Anesthesiology
All Tech Innovators: John A. Kellum Jr
Kai Singbartl
Date Submitted: 2008-06-30
Collections: Regenerative Medicine

MicFly: Rapid, Single-Cell Phenotyping and Absolute Quantification of Bacterial Microbiota

06270

MicFly integrates surface antibody binding with HCR-based DNA/RNA identity in single bacteria via flow cytometry for absolute quantification.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Immunology
Gastroenterology
Therapeutic Indications: Inflammatory bowel disease
Inflammation - General
Chrohn's Disease
Tags: Pediatrics
Precision medicine
Critical Care
Lead Inventor: Timothy Hand
Department: Med-Pediatrics
All Tech Innovators: Darryl A. Abbott
William H. DePas
Timothy Wesley Hand
Date Submitted: 2023-01-23

Novel Approach to Overcome Biofouling in Biosensors

05784

Two-electrode correction boosts label-free biosensor accuracy by masking biofouling, enabling simultaneous multi-target detection.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Infectious Disease
Lead Inventor: Prashant Kumta
Department: Bioengineering
All Tech Innovators: Moni Kanchan Datta
Prashant N. Kumta
Sangeetha Kunjukunju
Date Submitted: 2021-08-16

Advanced Methods for Diagnosing Prostate Cancer and Predicting Relapse

02406

CNV-based genome analysis predicts prostate cancer progression and relapse, enabling personalized diagnostics and targeted treatment planning.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Oncology
Therapeutic Indications: Prostate cancer / adenocarcinoma
Tags: Precision medicine
Clinical Decision Support
Lead Inventor: Jianhua Luo
Department: Med-Pathology
All Tech Innovators: Jianhua Luo
George Michalopoulos
Joel B. Nelson
Technology Readiness Level: 5. Analytical validation
Date Submitted: 2011-02-15

Level of Reactive Oxigen Species in Myeloid-Derived Suppressor Cells Predicts Clinical Responses to Interferon Therapy

02745

Predicting interferon therapy response via a single-dose MDSC ROS/pSTAT3 marker test guides personalized cancer treatment decisions.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Lead Inventor: Larisa Geskin
Department: Med-Dermatology
All Tech Innovators: Oleg Eugenievich Akilov
Larisa J. Geskin
Date Submitted: 2012-04-12

New Test Can Predict Immunotherapy Responders for Broader Range of Cancers than Current Tools

06200

IGR burden helps predict immunotherapy responders beyond current TMB tools, aiding broader cancer types and low-TMB cases.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Oncology
Lead Inventor: Xiaosong Wang
Department: Med-Pathology
All Tech Innovators: Xiaosong Wang
Date Submitted: 2022-10-31
Collections: Women's & Reproductive Health

Targeting Highly Tumor-specific Long Non-coding RNAs for Cancer Diagnosis, Prognosis, and Therapy

04518

Profile of cancer-linked long non-coding RNAs as biomarkers and therapeutic targets, enabling diagnosis, prognosis, and treatment.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Oncology
Therapeutic Indications: Ductal carcinoma (Breast cancer)
Lead Inventor: Da Yang
Department: Pharm-Pharmaceutical Science
All Tech Innovators: Zehua Wang
Da Yang
Date Submitted: 2018-02-14
Collections: Women's & Reproductive Health

Novel Salivary Biomarker for Cognitive Impairment

07426

Saliva-based sTREM2 biomarker enables noninvasive early detection of cognitive impairment and dementia risk.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Neuroscience
Therapeutic Indications: Alzheimer's Disease
Tags: Biomarker
In Vitro Diagnostic
Life Science
Lead Inventor: Tharick Ali Pascoal
Department: Med-Psychiatry
All Tech Innovators: Tharick Ali Pascoal
Daniel Robert Clark
Date Submitted: 2025-12-09

Novel Biomarker for Peridontal Disease

07268

Saliva-based sTREM2 biomarker enables noninvasive early detection of periodontal disease, guiding implant/surgical decisions.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Immunology
Therapeutic Indications: Inflammation - General
Tags: Biomarker
In Vitro Diagnostic
Life Science
Lead Inventor: Daniel Clark
Department: Dent Med-Periodontics/Preventive Dentistry
All Tech Innovators: Tharick Ali Pascoal
Daniel Robert Clark
Date Submitted: 2025-07-29
Collections: Regenerative Medicine
Women's & Reproductive Health

Instrument-Free Assay for In-Clinic Detection of Bladder or Prostate Cancer

03825

Colorimetric, instrument-free urine test detects bladder/prostate cancer via MMP-2/9–triggered Fe(II) release and Fenton reaction.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Oncology
Therapeutic Indications: Prostate cancer / adenocarcinoma
Lead Inventor: Abhinav Acharya
Department: Chem/Petroleum Engineering
All Tech Innovators: Abhinav Prakash Acharya
Steven R. Little
Tatum Varut Tarin
Date Submitted: 2016-02-09

Rapid Detection of Recent Flavivirus Infections Using IgG3 Anti-NS1

03819

IgG3-NS1 flavivirus assay detects recent infections within two weeks, reducing cross-reactivity across-bearing platforms (ELISA/Luminex).

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Infectious Disease
Therapeutic Indications: Other
Lead Inventor: Ernesto Marques
Department: GSPH-Infectious Diseases & Microbiology
All Tech Innovators: Ernesto Torres De Azeved Marques Jr
Eduardo Nascimento
Date Submitted: 2016-02-02

Automated Nuclei Segmentation for Disease Detection

03193

Automated nuclei segmentation for cancer diagnosis boosts speed and accuracy, enabling unbiased epithelial labeling and biomarker discovery.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Therapeutic Indications: Esophageal cancer
Lead Inventor: Virginia Burger
Department: Med-Computational and Systems Biology
All Tech Innovators: Virginia M. Burger
Srinivas C. Chennubhotla
Date Submitted: 2013-12-10

Novel Method of Idiopathic Pulmonary Fibrosis (IPF) Detection

01838

Urine-based MMP activation peptide detection correlates with IPF, enabling earlier diagnosis and flare prediction via ELISA.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Respiratory
Therapeutic Indications: Pulmonary fibrosis
Lead Inventor: Tim Oury
Department: Med-Pathology
All Tech Innovators: Jan J. Enghild
Naftali Kaminski
Tim David Oury MD, PhD
Date Submitted: 2008-09-25

Cancer Driver Gene Signatures for Precision Oncology and Immunotherapy

04188

Comprehensive driver-SGA signatures database guides precision oncology and immunotherapy by predicting drug response and immune status.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Lead Inventor: Xinghua Lu
Department: Med-Biomedical Informatics
All Tech Innovators: Chunhui Cai
Xueer Chen
Gregory F. Cooper
Date Submitted: 2017-03-09

Targeting Chromosomal Rearrangements for Cancer Treatment

03641

Targeting fusion gene-driven cancers with genome-editing therapies for precise, breakpoint-specific treatment and improved outcomes.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Therapeutic Indications: Hodgkin Lymphoma
Chronic Myeloid Leukemia (CML)
Chronic Lymphocytic Leukemia (CLL)
Lead Inventor: Jianhua Luo
Department: Med-Pathology
All Tech Innovators: Zhanghui Chen
Jianhua Luo
George Michalopoulos
Date Submitted: 2015-06-09
Collections: Women's & Reproductive Health

Novel Metabolomic Markers in Sepsis and Pneumonia

02808

Metabolomic profiling links sepsis/pneumonia outcomes to distinct biomarkers, revealing early pathways and candidate survival markers.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Infectious Disease
Respiratory
Therapeutic Indications: Sepsis
Pneumococcal
Lead Inventor: Christopher Seymour
Department: Med-Critical Care Medicine
All Tech Innovators: John A. Kellum Jr
Christopher W. Seymour
Date Submitted: 2012-06-12

Rapid Diagnostic Tool for Tuberculosis

06426

Rapid, affordable TB diagnostic using SWCNT-based FETs detects MTB antigen 85B in minutes with fg/mL sensitivity.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Infectious Disease
Tags: In Vitro Diagnostic
Life Science
Public Health
Lead Inventor: Alexander Star
Department: Chemistry
All Tech Innovators: Michael R. Shurin
Alexander Star
Jieyu Wang
Date Submitted: 2023-06-09