Technology Type

Diagnostic/Assay

93 results

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Novel Diagnostic Biomarker for Alzheimer's Disease

06770

Ultrasensitive CSF assay detects early pre-tangle soluble tau assemblies, enabling earlier Alzheimer’s diagnosis and targeted therapies.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Neuroscience
Therapeutic Indications: Alzheimer's Disease
Lead Inventor: Thomas Karikari
Department: Med-Psychiatry
All Tech Innovators: Eric E. Abrahamson
Milos Dragan Ikonomovic MD
Thomas K. Karikari
Date Submitted: 2024-06-10

Seeing Blood Flow One Cell at a Time: A Dye-Free Way to Map Retinal Circulation

07547

Dye-free OCTA method tracks single red blood cells in retinal vessels, mapping 3D flow with two velocity metrics.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Ophthalmology
Therapeutic Indications: Retinal vein occulsion (RVO)
Glaucoma
Diabetic retinopathy
Tags: Aging
Minimally invasive
Lead Inventor: Shaohua Pi
Department: Med-Ophthalmology
All Tech Innovators: Shaohua Pi
Bingjie Wang
Lingyun Wang
Technology Readiness Level: 3. Development of test
Date Submitted: 2026-04-09

PEA-Q: The First Validated Tool to Measure Pregnancy-Specific Eating and Weight Attitudes

07658

Validated 11-item PEA-Q measures pregnancy-specific eating attitudes across gestation; brief, reliable screening and outcome tool.

Technology Type: Diagnostic/Assay
Therapeutic Areas: Reproductive Health
Therapeutic Indications: Obstetrics
Tags: Women's Health
Lead Inventor: Michele Levine
Department: Med-Psychiatry
All Tech Innovators: Christine C. Call
Rachel Pearl Kolko Conlon
Riley Jane Jouppi
Technology Readiness Level: 4. Proof of concept
Date Submitted: 2026-06-25
Collections: Women's & Reproductive Health

Highly Accurate Serological Biomarker for Early Detection of Nasopharyngeal Carcinoma

05923

A serological panel detects EBV EBNA1 IgA with 100% sensitivity/specificity, enabling pre-diagnostic NPC risk screening.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Therapeutic Indications: Nasopharyngeal carcinoma (NPC)
Solid tumor
Lead Inventor: Kathy Ho Yen Shair
Department: Med-Microbiology and Molecular Genetics
All Tech Innovators: Kathy Ho Yen Shair
Jian-Min Yuan
Date Submitted: 2021-12-20

ASSIST Functional Performance Index: Enhancing Everyday Functionality with Smart Technology

06381

AFPI gauges how smart tech aids daily tasks across six domains, guiding support to boost independence for disabled and older adults.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Lead Inventor: Dan Ding
Department: SHRS-Rehab Sci & Tech
All Tech Innovators: Dan Ding
Andrea Dawn Fairman
Lindsey Lee Morris
Date Submitted: 2023-04-20

Post-Cardiac Arrest Classification Mobile and Web App

06035

Real-time PCAC scoring app for bedside cardiac arrest patients, improving outcomes, workflow, and cross-center comparisons.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Cardiovascular
Therapeutic Indications: Other
Lead Inventor: Ankur Doshi
Department: Med-Emergency Medicine
All Tech Innovators: Gabriel Lucas Diamond
Ankur Ashok Doshi
Date Submitted: 2022-05-19
Collections: Cardiometabolic

Airway Biomarker Panel and Targeted Intervention Strategy for Steroid-Refractory Severe Asthma

07670

Airway gene/glycosylation biomarker panel stratifies steroid-refractory severe asthma and enables targeted knockdown/inhibition.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Respiratory
Therapeutic Indications: Asthma
Tags: Artificial intelligence (AI)
Autoimmune
Genetics
Lead Inventor: Anuradha Ray
Department: Med-Medicine
All Tech Innovators: Jishnu Das
Marc C. Gauthier
Sagar Kale
Technology Readiness Level: 3. Development of test
Date Submitted: 2026-07-01
Collections: Healthcare AI

TempoGap: A Molecular "Recovery Clock" for Predicting Outcomes in Critical Illness

07583

TempoGap predicts immune recovery time from blood data, quantifies its gap to clinical timeline, signaling risk and guiding care.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Infectious Disease
Intensive Care
Therapeutic Indications: Sepsis
Covid-19
Trauma
Tags: Machine learning
Platform Technology
Algorithm
Lead Inventor: TeDing Chang
Department: Med-Surgery
All Tech Innovators: Timothy R. Billiar
TeDing Chang
Hamed Moheimani
Technology Readiness Level: 4. Proof of concept
Date Submitted: 2026-04-29

Novel Biomarker for Cervical Spondylotic Myelopathy

07261

Blood-based biomarker panel with ML predicts CSM diagnosis, severity, prognosis, and treatment response, reducing invasive testing.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Neuroscience
Tags: Aging
Biomarker
Clinical Decision Support
Lead Inventor: Nitin Agarwal
Department: Med-Neurological Surgery
All Tech Innovators: Nitin Agarwal
Sameer Agnihotri
David Kojo Hamilton
Date Submitted: 2025-07-24

Novel Biomarker Tools for Tauopathies

06769

Antibody-based blood tests detect phosphorylated tau, enabling early tauopathy diagnosis and tracking treatment responses.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Neuroscience
Therapeutic Indications: Alzheimer's Disease
Lead Inventor: Thomas Karikari
Department: Med-Psychiatry
All Tech Innovators: Thomas K. Karikari
Xuemei Zeng
Date Submitted: 2024-06-06

Streamlined Resource–Efficient Assay for Amyloid-β

06792

A streamlined IP-MS assay uses a common buffer to quantify plasma amyloid-β biomarkers, enabling affordable, noninvasive AD monitoring.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Neuroscience
Therapeutic Indications: Alzheimer's Disease
Tags: In Vitro Diagnostic
Life Science
Lead Inventor: Thomas Karikari
Department: Med-Psychiatry
All Tech Innovators: Yijun Chen
Thomas K. Karikari
Nathan A. Yates
Date Submitted: 2024-07-05

B Cell-Based Biomarker for Detecting Acute Renal Transplant Rejection

06574

Noninvasive B-cell biomarker via spectral flow cytometry and ML predicts acute/subclinical renal transplant rejection with high accuracy.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Nephrology
Immunology
Therapeutic Indications: Other
Lead Inventor: David Rothstein
Department: Med-Surgery
All Tech Innovators: Aravind Cherukuri
David Mark Rothstein
Date Submitted: 2023-11-27

Integrated AI and Sensing System for Pulmonary Disease Evaluation

06395

Integrated AI-powered smartphone system PTEase enables remote pulmonary disease evaluation via airway measurements and ML biomarkers.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Respiratory
Lead Inventor: Wei Gao
Department: Electrical and Computer Engineering
All Tech Innovators: Wei Chen
Erick Forno
Wei Gao
Date Submitted: 2023-05-03
Collections: Healthcare AI

Novel Approach to Rapid Hearing Loss Assessment

06185

Non-invasive EEG-based test blends tailored sounds and algorithms to objectively diagnose perception-related hearing loss.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Otolaryngology
Therapeutic Indications: Hearing Loss
Lead Inventor: Aravindakshan Parthasarathy
Department: SHRS-Commu Science & Disorders
All Tech Innovators: Edward L. Bartlett
Satyabrata Parida
Aravindakshan Parthasarathy
Date Submitted: 2022-10-16

Decoupling Immunotherapy Toxicity from Efficacy: GPR183 Biomarker and Therapeutic Platform

07600

GPR183-based biomarker platform predicts irAEs, separates toxicity from efficacy, and enables combination therapies to boost cancer immunity.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Therapeutic Indications: Colorectal cancer (CRC)
Solid tumor
Lung cancer - other
Tags: Genetics
Immuno-oncology
Lead Inventor: Abigail Overacre
Department: Med-Immunology
All Tech Innovators: Abigail Elise Overacre
Dipyaman Patra
Technology Readiness Level: 3. Development of test
Date Submitted: 2026-05-15

Rapid Electrochemical Screen for Illicit Drugs

06703

Automated 96-sensor electrolyte-gated FET platform rapidly screens illicit drugs with high-throughput, streamlined lab workflows.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Mental and Behavioral Health
Lead Inventor: Alexander Star
Department: Chemistry
All Tech Innovators: Zhengru Liu
Alexander Star
Date Submitted: 2024-03-27

A Novel Therapeutic Biomarker for Metabolic Liver Disease

06324

Identifies PNPLA3 rs738409 variant driving MAFLD via ferroptosis; enables targeted therapies, screening, and safer liver transplantation.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Hepatology
Therapeutic Indications: End-Stage liver disease (ESLD)
Cirrhosis
Tags: Drug Discovery - Target
Life Science
Liver Disease
Lead Inventor: Alejandro Soto Gutierrez
Department: Med-Pathology
All Tech Innovators: Abhinav Achreja
Olamide Animasahun
Rodrigo Machado Florentino
Date Submitted: 2023-03-01
Collections: Cardiometabolic

RNA- and DNA-Based Assays for Predicting Paclitaxel Resistance in Triple Negative Breast Cancer

05224

RNA- and DNA-based assays identify a TNBC-specific fusion linked to paclitaxel resistance, enabling therapy pivots.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Therapeutic Indications: Ductal carcinoma (Breast cancer)
Lead Inventor: Xiaosong Wang
Department: Med-Pathology
All Tech Innovators: Xiaosong Wang
Date Submitted: 2020-01-17
Collections: Women's & Reproductive Health

Resolving Diagnostic Discrepancies in Multiple Myeloma Patients

04607

Magnetic bead-based depletion removes therapeutic monoclonal antibodies, reducing false positives in MM diagnostics and treatment monitoring.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Oncology
Hematology
Tags: Coating
Immuno-oncology
Lead Inventor: Sarah Wheeler
Department: Med-Pathology
All Tech Innovators: Li Liu
Michael R. Shurin
Sarah Elizabeth Wheeler
Date Submitted: 2018-04-26

Epstein-Barr Circular RNA as a Novel Biomarker of EBV-Related Cancers

04470

Stable circBART circular RNAs enable rapid, inexpensive EBV cancer detection, improving accuracy and early diagnosis.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Oncology
Infectious Disease
Therapeutic Indications: Lymphoma
Herpes
Lead Inventor: Patrick Moore
Department: Med-Pathology
All Tech Innovators: Yuan Chang
Patrick S. Moore
Tuna Toptan
Date Submitted: 2018-01-02

Pittsburgh Fatigability Scale (PFS)

03429

A validated 10-item, self-administered scale measuring physical and mental fatigability in adults 60+, predicting mobility risk.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Endocrinology and Metabolic Diseases
Tags: Aging
Human performance
Platform Technology
Lead Inventor: Nancy Glynn
Department: GSPH-Epidemiology
All Tech Innovators: Scott Richard Beach
Robert M. Boudreau
Nancy W. Glynn
Date Submitted: 2014-10-22
Collections: Cardiometabolic

Novel Assessment for Cutaneous T Cell Lymphoma

02958

Proposes a genetic CTCL diagnostic signature (TOX, RUNX3, GATA3) to diagnose, gauge severity, and tailor treatment.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Therapeutic Indications: Melanoma
Lead Inventor: Larisa Geskin
Department: Med-Dermatology
All Tech Innovators: Brittany Lynn O'Neill Dulmage
Louis D. Falo Jr
Larisa J. Geskin
Date Submitted: 2013-01-08

Non-Invasive Detection of HPV+ and Throat Cancers

06558

Non-invasive device irrigates lesions to harvest cfDNA for HPV+ throat cancer risk via NGS, reducing biopsies.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Oncology
Lead Inventor: Jose Zevallos
Department: Med-Otolaryngology
All Tech Innovators: Jose P. Zevallos
Date Submitted: 2023-11-03
Collections: Women's & Reproductive Health

Novel Biosensor to Detect Fentanyl Exposure

06287

Ultra-sensitive sc-SWCNT FET biosensor detects norfentanyl in biofluids within minutes, enabling rapid, portable fentanyl exposure screening.

Technology Type: Diagnostic/Assay
Therapeutic Areas: Other
Lead Inventor: Alexander Star
Department: Chemistry
All Tech Innovators: Wenting Shao
Alexander Star
Date Submitted: 2023-02-09

SWeeTT: Solitary Wave-based easily-employable Trans-palpebral Tonometer

04573

SWeeTT enables easy, at-home, trans-palpebral intraocular pressure monitoring with daily data and clinician connectivity.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Ophthalmology
Lead Inventor: Piervincenzo Rizzo
Department: Civil & Environmental Engineering
All Tech Innovators: Amir Nasrollahi
Piervincenzo Rizzo
Date Submitted: 2018-03-31

Biomarkers for Diagnosis of Ear and Sinus Infections

07147

Novel nasal IL-1a biomarker plus symptom algorithm improves pediatric bacterial sinusitis diagnosis, guiding antibiotic use.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Otolaryngology
Tags: Biomarker
Clinical Decision Support
Life Science
Lead Inventor: Nader Shaikh
Department: Med-Pediatrics
All Tech Innovators: Nader Shaikh
Date Submitted: 2025-04-11

MicFly: Rapid, Single-Cell Phenotyping and Absolute Quantification of Bacterial Microbiota

06270

MicFly couples surface antibody binding with single-cell identity via HCR and flow cytometry for absolute bacterial quantification.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Immunology
Gastroenterology
Therapeutic Indications: Inflammatory bowel disease
Inflammation - General
Chrohn's Disease
Tags: Pediatrics
Precision medicine
Critical Care
Lead Inventor: Timothy Hand
Department: Med-Pediatrics
All Tech Innovators: Darryl A. Abbott
William H. DePas
Timothy Wesley Hand
Date Submitted: 2023-01-23

MATS Proteomics Test

05511

Hybrid mass-spectrometry + ML platform enabling absolute, high-throughput proteome quantitation for biomarker discovery and clinical diagnostics.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Lead Inventor: Kunhong Xiao
Department: Med-Pharmacology and Chemical Biology
All Tech Innovators: Fei Fang
Kunhong Xiao
Date Submitted: 2020-09-24

Eomesodermin as a Biomarker for Allograft Rejection

03456

Eomesodermin as a noninvasive biomarker predicts transplant rejection risk by monitoring memory T cell activity to guide therapy.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Surgery
Immunology
Therapeutic Indications: Other
Lead Inventor: Mohamed Ezzelarab
Department: Med-Surgery
All Tech Innovators: Mohamed Borhami Ezzelarab
Angus W. Thomson
Date Submitted: 2014-11-25

Fusion Gene-Based Machine Learning Tool Enhances Prediction of Prostate Cancer Clinical Outcomes

06089

Fusion-gene based machine learning boosts prostate cancer recurrence predictions using 14 gene signatures across multiple cohorts.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Urology
Oncology
Therapeutic Indications: Prostate cancer / adenocarcinoma
Tags: Genetics
Lead Inventor: Jianhua Luo
Department: Med-Pathology
All Tech Innovators: Shuchang Liu
Jianhua Luo
George Michalopoulos
Date Submitted: 2022-07-01

Early Warning System for Preventing Necrotizing Enterocolitis (NEC) in Preterm Infants

05327

AI-driven NEC risk predictor for preterm infants using stool microbiome data, clinical features, enabling early intervention. 132 characters

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Gastroenterology
Therapeutic Indications: Other
Tags: Machine learning
Lead Inventor: Thomas Hooven
Department: Med-Pediatrics
All Tech Innovators: Thomas Hooven
Yun Chao Lin
Ansaf Salleb-Aouissi
Date Submitted: 2020-04-29
Collections: Healthcare AI

Methods for Predicting and Monitoring Responsiveness to Multiple Myeloma Therapy

03913

A biomarker-based method monitors Ser288-phosphorylated hXBP1s to predict and gauge myeloma therapy response.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Therapeutic Indications: Multiple Myeloma
Tags: Drug Repurposing
Lead Inventor: Hongjiao Ouyang
Department: Dent Med-Oral Biology
All Tech Innovators: Hongjiao Ouyang
Date Submitted: 2016-04-19

Novel Biomarker for Personalizing Cancer

06959

Personalized cancer immunotherapy: a 10-gene type-I IFN and exhaustion signature predicts response to anti-PD-1+LAG-3 therapy.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Tags: Biomarker
Personalized Medicine
Life Science
Lead Inventor: Robert Ferris
All Tech Innovators: Robert Louis Ferris
Housaiyin Li
Lazar Nikola Vujanovic
Date Submitted: 2024-11-06

A Novel Neoplastic Fusion Transcript Predicts Sensitivity to the MEK Inhibitor Trametinib in More Aggressive and Metastatic Breast Cancers

05317

Fusion RAD51AP1-DYRK4 predicts trametinib sensitivity in aggressive/metastatic breast cancers, enabling targeted MEK inhibitor therapy.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Therapeutic Indications: Ductal carcinoma (Breast cancer)
Tags: Precision medicine
Personalized Medicine
Women's Health
Lead Inventor: Xiaosong Wang
Department: Med-Pathology
All Tech Innovators: Chia Chia Liu
Xiaosong Wang
Date Submitted: 2020-04-22
Collections: Women's & Reproductive Health

Apathy Evaluation Scale (AES): A Standardized Tool for Measuring Lack of Motivation in Adults and the Elderly

05180

AES is a validated 18-item tool measuring apathy across behavioral, cognitive, and emotional domains with self, informant, and clinician versions.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Mental and Behavioral Health
Lead Inventor: Robert Marin
Department: Med-Psychiatry
All Tech Innovators: Robert S. Marin
Date Submitted: 2019-11-22

Novel Biomarker to Detect CMV T Cell Immunity

04855

KLRG1-based assay predicts CMV T cell immunity in transplant patients, enabling targeted antiviral therapy.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Immunology
Infectious Disease
Lead Inventor: John McDyer
Department: Med-Medicine
All Tech Innovators: Akihiko Hoji
John Francis McDyer
Iulia-Dana Popescu
Date Submitted: 2019-01-09

AOM-SOS Version 5.0: Enhanced Psychometric Scale for Acute Otitis Media

04070

Enhanced AOM-SOS 5.0: six-point pediatric otitis media symptom scale with improved reliability for clinical use and research.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Otolaryngology
Therapeutic Indications: Other
Lead Inventor: Nader Shaikh
Department: Med-Pediatrics
All Tech Innovators: Alejandro Hoberman
Jack L. Paradise
Nader Shaikh
Date Submitted: 2016-11-07

Personalized Pain Management: Predicting Chronic Pain Post-Mastectomy

02280

Personalized post-mastectomy pain risk profiling using genetic and psychosocial data to tailor perioperative care.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Neuroscience
Oncology
Therapeutic Indications: Pain
Ductal carcinoma (Breast cancer)
Tags: Genetics
Personalized Medicine
Clinical Decision Support
Lead Inventor: Inna Belfer
Department: GSPH-Human Genetics
All Tech Innovators: Inna Belfer
Feng Dai
Technology Readiness Level: 4. Proof of concept
Date Submitted: 2010-08-22
Collections: Women's & Reproductive Health

Novel Therapy to Prevent Liver Disease

05722

Targeting ferroptosis to prevent PNPLA3 rs738409:G-linked liver cirrhosis, offering non-invasive therapy and reduced transplant need.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Hepatology
Therapeutic Indications: Non-alcoholic steatohepatitis (NASH)
Cirrhosis
Tags: Genetics
Lead Inventor: Alejandro Soto Gutierrez
Department: Med-Pathology
All Tech Innovators: Abhinav Achreja
Olamide Animasahun
Rodrigo Machado Florentino
Date Submitted: 2021-06-10
Collections: Cardiometabolic

Urinary Biomarkers for Predicting Long-Term Dialysis

01776

Urinary hyaluronic acid as a non-invasive biomarker predicts long-term dialysis risk after AKI, enabling early CKD prevention.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Intensive Care
Nephrology
Lead Inventor: Kai Singbartl
Department: Department of Anesthesiology
All Tech Innovators: John A. Kellum Jr
Kai Singbartl
Date Submitted: 2008-06-30
Collections: Regenerative Medicine

Novel Approach to Overcome Biofouling in Biosensors

05784

Two-electrode correction boosts label-free biosensor accuracy by separating biofouling from target signals for rapid, multi-analyte detection.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Infectious Disease
Lead Inventor: Prashant Kumta
Department: Bioengineering
All Tech Innovators: Moni Kanchan Datta
Prashant N. Kumta
Sangeetha Kunjukunju
Date Submitted: 2021-08-16

Advanced Methods for Diagnosing Prostate Cancer and Predicting Relapse

02406

CNV-based genome analysis predicts prostate cancer progression and relapse, enabling personalized diagnostics and targeted treatment planning.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Oncology
Therapeutic Indications: Prostate cancer / adenocarcinoma
Tags: Precision medicine
Clinical Decision Support
Lead Inventor: Jianhua Luo
Department: Med-Pathology
All Tech Innovators: Jianhua Luo
George Michalopoulos
Joel B. Nelson
Technology Readiness Level: 5. Analytical validation
Date Submitted: 2011-02-15

Level of Reactive Oxigen Species in Myeloid-Derived Suppressor Cells Predicts Clinical Responses to Interferon Therapy

02745

Predicting interferon therapy response via a single-dose MDSC ROS/pSTAT3 marker test guides personalized cancer treatment decisions.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Lead Inventor: Larisa Geskin
Department: Med-Dermatology
All Tech Innovators: Oleg Eugenievich Akilov
Larisa J. Geskin
Date Submitted: 2012-04-12

New Test Can Predict Immunotherapy Responders for Broader Range of Cancers than Current Tools

06200

IGR burden helps predict immunotherapy responders beyond current TMB tools, aiding broader cancer types and low-TMB cases.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Oncology
Lead Inventor: Xiaosong Wang
Department: Med-Pathology
All Tech Innovators: Xiaosong Wang
Date Submitted: 2022-10-31
Collections: Women's & Reproductive Health

Novel Biomarker for Peridontal Disease

07268

Saliva-based sTREM2 biomarker enables noninvasive early detection of periodontal disease, guiding implant/surgical decisions.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Immunology
Therapeutic Indications: Inflammation - General
Tags: Biomarker
In Vitro Diagnostic
Life Science
Lead Inventor: Daniel Clark
Department: Dent Med-Periodontics/Preventive Dentistry
All Tech Innovators: Tharick Ali Pascoal
Daniel Robert Clark
Date Submitted: 2025-07-29
Collections: Regenerative Medicine

Instrument-Free Assay for In-Clinic Detection of Bladder or Prostate Cancer

03825

Colorimetric, instrument-free urine test detects bladder/prostate cancer via MMP-2/9–triggered Fe(II) release and Fenton reaction.

Technology Type: Diagnostic/Assay
Technology Subtype: Other Diagnostic/Assay
Therapeutic Areas: Oncology
Therapeutic Indications: Prostate cancer / adenocarcinoma
Lead Inventor: Abhinav Acharya
Department: Chem/Petroleum Engineering
All Tech Innovators: Abhinav Prakash Acharya
Steven R. Little
Tatum Varut Tarin
Date Submitted: 2016-02-09

Rapid Detection of Recent Flavivirus Infections Using IgG3 Anti-NS1

03819

IgG3-NS1 flavivirus assay detects recent infections within two weeks, reducing cross-reactivity across-bearing platforms (ELISA/Luminex).

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Infectious Disease
Therapeutic Indications: Other
Lead Inventor: Ernesto Marques
Department: GSPH-Infectious Diseases & Microbiology
All Tech Innovators: Ernesto Torres De Azeved Marques Jr
Eduardo Nascimento
Date Submitted: 2016-02-02

Automated Nuclei Segmentation for Disease Detection

03193

Automated nuclei segmentation for cancer diagnosis boosts speed and accuracy, enabling unbiased epithelial labeling and biomarker discovery.

Technology Type: Diagnostic/Assay
Technology Subtype: Biomarker
Therapeutic Areas: Oncology
Therapeutic Indications: Esophageal cancer
Lead Inventor: Virginia Burger
Department: Med-Computational and Systems Biology
All Tech Innovators: Virginia M. Burger
Srinivas C. Chennubhotla
Date Submitted: 2013-12-10

Novel Transcriptional Signature for Chlamydial PID

03188

Novel transcriptional signature enables low-cost, minimally invasive detection of asymptomatic chlamydial PID and endometritis.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Reproductive Health
Infectious Disease
Tags: Autoimmune
Lead Inventor: Catherine O'Connell
Department: Pediatrics
All Tech Innovators: Lee Antoinette Darville
Catherine Mary O'Connell
Xiaojing Zheng
Date Submitted: 2013-12-06
Collections: Women's & Reproductive Health

Novel Method of Idiopathic Pulmonary Fibrosis (IPF) Detection

01838

Urine-based MMP activation peptide detection correlates with IPF, enabling earlier diagnosis and flare prediction via ELISA.

Technology Type: Diagnostic/Assay
Technology Subtype: In vitro Diagnostic
Therapeutic Areas: Respiratory
Therapeutic Indications: Pulmonary fibrosis
Lead Inventor: Tim Oury
Department: Med-Pathology
All Tech Innovators: Jan J. Enghild
Naftali Kaminski
Tim David Oury MD, PhD
Date Submitted: 2008-09-25